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Cellosaurus F-137 (CVCL_1Q45)

[Text version]
Cell line name F-137
Synonyms F 137; F137
Accession CVCL_1Q45
Resource Identification Initiative To cite this cell line use: F-137 (RRID:CVCL_1Q45)
Comments Problematic cell line: Contaminated. Shown to be a Jiyoye derivative (PubMed=4736620). Originally thought to originate from the lymph node of a male chronic lymphocytic leukemia patient.
Population: African; Nigerian.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Lys132Gln (c.394A>C); ClinVar=VCV000376628; Zygosity=Unspecified (from parent cell line).
Disease EBV-related Burkitt lymphoma (NCIt: C27694)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1317 (Jiyoye)
CVCL_1Q46 (G3.32.2)
Sex of cell Male
Age at sampling 7Y
Category Cancer cell line

PubMed=18623934; DOI=10.1093/jnci/39.4.745
Jensen E.M., Korol W., Dittmar S.L., Medrek T.J.
Virus containing lymphocyte cultures from cancer patients.
J. Natl. Cancer Inst. 39:745-754(1967)

PubMed=5287057; DOI=10.1093/jnci/47.6.1203
Steel C.M., McBeath S., O'Riordan M.L.
Human lymphoblastoid cell lines. II. Cytogenetic studies.
J. Natl. Cancer Inst. 47:1203-1214(1971)

PubMed=4736620; DOI=10.1111/j.1469-1809.1973.tb00588.x
Povey S., Gardiner S.E., Watson B., Mowbray S., Harris H., Arthur E., Steel C.M., Blenkinsop C., Evans H.J.
Genetic studies on human lymphoblastoid lines: isozyme analysis on cell lines from forty-one different individuals and on mutants produced following exposure to a chemical mutagen.
Ann. Hum. Genet. 36:247-266(1973)

PubMed=1180485; DOI=10.1111/j.1469-1809.1975.tb00105.x
Arthur E., Steel C.M., Evans H.J., Povey S., Watson B., Harris H.
Genetic studies on human lymphoblastoid cell lines: isozyme and cytogenetic heterogeneity in a cell line, with evidence for localization of the Pep A locus in man.
Ann. Hum. Genet. 39:33-42(1975)

Cell line databases/resources cancercelllines; CVCL_1Q45
Encyclopedic resources Wikidata; Q54833024
Entry history
Entry creation08-Jul-2015
Last entry update05-Oct-2023
Version number16