ID   HOS-CD4-Fusin
AC   CVCL_1D99
SY   HOS-CD4.Fusin
DR   BEI_Resources; ARP-3319
DR   cancercelllines; CVCL_1D99
DR   Wikidata; Q54890169
RX   PubMed=8649511;
CC   Population: Caucasian.
CC   Sequence variation: Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg156Pro (c.467G>C); ClinVar=VCV000634768; Zygosity=Homozygous (from parent cell line).
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:1678; CD4.
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:2561; CXCR4.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P0A9M5; Escherichia coli gpt.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Derived from site: In situ; Bone, right femur; UBERON=UBERON_0000981.
DI   NCIt; C9145; Osteosarcoma
DI   ORDO; Orphanet_668; Osteosarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_W650 ! HOS-CD4
SX   Female
AG   13Y
CA   Cancer cell line
DT   Created: 08-07-15; Last updated: 19-12-24; Version: 14
//
RX   PubMed=8649511; DOI=10.1038/381661a0;
RA   Deng H.-K., Liu R., Ellmeier W., Choe S., Unutmaz D., Burkhart M.,
RA   Di Marzio P., Marmon S., Sutton R.E., Hill C.M., Davis C.B.,
RA   Peiper S.C., Schall T.J., Littman D.R., Landau N.R.;
RT   "Identification of a major co-receptor for primary isolates of
RT   HIV-1.";
RL   Nature 381:661-666(1996).
//