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Cellosaurus HOS-CD4-CCR2b (CVCL_1D95)

[Text version]
Cell line name HOS-CD4-CCR2b
Synonyms HOS-CD4-CCR-2B; HOS-CD4.CCR-2B; HOS.CD4.CCR2b
Accession CVCL_1D95
Resource Identification Initiative To cite this cell line use: HOS-CD4-CCR2b (RRID:CVCL_1D95)
Comments Population: Caucasian.
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:1678; CD4.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:1603; CCR2 (Note=Isoform B).
Genetic integration: Method=Transfection; Gene=UniProtKB; P0A9M5; Escherichia coli gpt.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Derived from site: In situ; Bone, right femur; UBERON=UBERON_0000981.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg156Pro (c.467G>C); ClinVar=VCV000634768; Zygosity=Homozygous (from parent cell line).
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_W650 (HOS-CD4)
Sex of cell Female
Age at sampling 13Y
Category Cancer cell line
Publications

PubMed=8649511; DOI=10.1038/381661a0
Deng H.-K., Liu R., Ellmeier W., Choe S., Unutmaz D., Burkhart M., Di Marzio P., Marmon S., Sutton R.E., Hill C.M., Davis C.B., Peiper S.C., Schall T.J., Littman D.R., Landau N.R.
Identification of a major co-receptor for primary isolates of HIV-1.
Nature 381:661-666(1996)

Cross-references
Cell line collections (Providers) BEI_Resources; ARP-3315
Cell line databases/resources cancercelllines; CVCL_1D95
Encyclopedic resources Wikidata; Q54890165
Entry history
Entry creation08-Jul-2015
Last entry update19-Dec-2024
Version number14