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Cellosaurus 293TT (CVCL_1D85)

[Text version]
Cell line name 293TT
Synonyms HEK293TT; NCI-293TT
Accession CVCL_1D85
Resource Identification Initiative To cite this cell line use: 293TT (RRID:CVCL_1D85)
Comments Characteristics: Engineered to overexpress the SV40 large T antigen. Was transfected with a constitutive T-antigen expression plasmid (PubMed=14694107).
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA).
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0063 (HEK293T)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
STR profile Source(s): ATCC=CRL-3467

Markers:
AmelogeninX
CSF1PO11,12,13
D5S8188,9
D7S82011
D13S31711,12,14
D16S5399,13
TH017,9.3
TPOX11
vWA16,19

Run an STR similarity search on this cell line
Web pages https://web.archive.org/web/20150923173827/http://www.ott.nih.gov/erma/nci-293tt-cell-line
Publications

PubMed=14694107; DOI=10.1128/JVI.78.2.751-757.2004; PMCID=PMC368835
Buck C.B., Pastrana D.V., Lowy D.R., Schiller J.T.
Efficient intracellular assembly of papillomaviral vectors.
J. Virol. 78:751-757(2004)

PubMed=23843634; DOI=10.1128/JVI.01189-13; PMCID=PMC3754014
Pastrana D.V., Ray U., Magaldi T.G., Schowalter R.M., Cuburu N., Buck C.B.
BK polyomavirus genotypes represent distinct serotypes with distinct entry tropism.
J. Virol. 87:10105-10113(2013)

Cross-references
Cell line collections (Providers) ATCC; CRL-3467
NCI-DTP; NCI-293TT
Encyclopedic resources Wikidata; Q54584162
Entry history
Entry creation08-Jul-2015
Last entry update10-Sep-2024
Version number16