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Cellosaurus U-CH11 (CVCL_1D67)

[Text version]
Cell line name U-CH11
Synonyms UCH11
Accession CVCL_1D67
Resource Identification Initiative To cite this cell line use: U-CH11 (RRID:CVCL_1D67)
Comments Population: Caucasian.
Doubling time: 10 days (PubMed=26183925); 15 days (Chordoma Foundation).
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Bone, sacrum; UBERON=UBERON_0003690.
Sequence variations
Disease Sacral chordoma (NCIt: C129927)
Chordoma (ORDO: Orphanet_178)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_VR46 ! U-CH11R
Sex of cell Male
Age at sampling 71Y
Category Cancer cell line
STR profile Source(s): PubMed=26183925

Markers:
AmelogeninX
CSF1PO10,11
D3S135815
D7S8209,10
D8S117913,16
D13S31714
D16S5399,11
D18S5114
Penta D9,12
Penta E7,14
TH016,9.3
TPOX8

Run an STR similarity search on this cell line
Web pages https://www.chordomafoundation.org/researchers/disease-models/u-ch11/
Publications

PubMed=26183925; DOI=10.1158/0008-5472.CAN-14-3270
von Witzleben A., Goerttler L.T., Marienfeld R., Barth H., Lechel A., Mellert K., Bohm M., Kornmann M., Mayer-Steinacker R., von Baer A., Schultheiss M., Flanagan A.M., Moller P., Bruderlein S., Barth T.F.E.
Preclinical characterization of novel chordoma cell systems and their targeting by pharmocological inhibitors of the CDK4/6 cell-cycle pathway.
Cancer Res. 75:3823-3831(2015)

PubMed=28515451; DOI=10.1038/s41598-017-02174-5; PMCID=PMC5435709
Jager D., Barth T.F.E., Bruderlein S., Scheuerle A., Rinner B., von Witzleben A., Lechel A., Meyer P., Mayer-Steinacker R., von Baer A., Schultheiss M., Wirtz C.R., Moller P., Mellert K.
HOXA7, HOXA9, and HOXA10 are differentially expressed in clival and sacral chordomas.
Sci. Rep. 7:2032-2032(2017)

Cross-references
Cell line collections (Providers) ATCC; CRL-3302 - Discontinued
Cell line databases/resources cancercelllines; CVCL_1D67
Encyclopedic resources Wikidata; Q54973613
Gene expression databases GEO; GSM1673857
GEO; GSM1673858
Entry history
Entry creation08-Jul-2015
Last entry update19-Dec-2024
Version number16