ID   HROC32
AC   CVCL_1D06
SY   HROC32P
DR   cancercelllines; CVCL_1D06
DR   CLS; 300818
DR   Cosmic; 2324290
DR   GEO; GSM1448079
DR   Wikidata; Q54895282
RX   PubMed=25574089;
RX   PubMed=25926053;
RX   PubMed=31601052;
CC   From: Linnebacher, Michael; University of Rostock; Rostock; Germany.
CC   Population: Caucasian.
CC   Doubling time: 32 +- 10.6 hours (PubMed=25574089); 30 hours (CLS=300818).
CC   HLA typing: A*01:01,02:01; B*08:01,03:01; C*07:01,14:02; DPB1*01:01,02:01; DQA1*01:02,05:01; DQB1*02:01,03:01; DRB1*03:01,11:01 (CLS=300818).
CC   Microsatellite instability: Stable (MSS) (PubMed=25926053).
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Ala (c.35G>C); ClinVar=VCV000045122; Zygosity=Unspecified (CLS=300818).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg282Trp (c.844C>T); ClinVar=VCV000012364; Zygosity=Unspecified (CLS=300818).
CC   Omics: Transcriptomics; Microarray.
CC   Derived from site: In situ; Colon, ascending; UBERON=UBERON_0001156.
ST   Source(s): CLS=300818; Direct_author_submission; PubMed=25926053
ST   Amelogenin: X
ST   CSF1PO: 14
ST   D13S317: 11,12 (Direct_author_submission)
ST   D13S317: 12 (CLS=300818; PubMed=25926053)
ST   D16S539: 11,12
ST   D18S51: 12
ST   D21S11: 31
ST   D3S1358: 15,17
ST   D5S818: 11,12 (CLS=300818; Direct_author_submission)
ST   D5S818: 12 (PubMed=25926053)
ST   D7S820: 8,11
ST   D8S1179: 12
ST   FGA: 18,19
ST   Penta D: 12
ST   Penta E: 10
ST   TH01: 8,9
ST   TPOX: 8,11
ST   vWA: 19
DI   NCIt; C4349; Colon adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_YD55 ! B-LCL-HROC32
OI   CVCL_1D07 ! HROC32 T3 M1
SX   Female
AG   82Y
CA   Cancer cell line
DT   Created: 08-07-15; Last updated: 10-04-25; Version: 24
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RX   PubMed=25926053; DOI=10.1038/ncomms8002;
RA   Medico, Enzo
RA   Russo, Mariangela
RA   Picco, Gabriele
RA   Cancelliere, Carlotta
RA   Valtorta, Emanuele
RA   Corti, Giorgio
RA   Buscarino, Michela
RA   Isella, Claudio
RA   Lamba, Simona
RA   Martinoglio, Barbara
RA   Veronese, Silvio
RA   Siena, Salvatore
RA   Sartore-Bianchi, Andrea
RA   Beccuti, Marco
RA   Mottolese, Marcella
RA   Linnebacher, Michael
RA   Cordero, Francesca
RA   Di Nicolantonio, Federica
RA   Bardelli, Alberto
RT   "The molecular landscape of colorectal cancer cell lines unveils
RT   clinically actionable kinase targets.";
RL   Nat. Commun. 6:7002.1-7002.10(2015).
//
RX   PubMed=31601052; DOI=10.3390/cancers11101520; PMCID=PMC6826890;
RA   Mullins, Christina Susanne
RA   Micheel, Bianca
RA   Matschos, Stephanie
RA   Leuchter, Matthias
RA   Burtin, Florian
RA   Krohn, Mathias
RA   Huhns, Maja
RA   Klar, Ernst
RA   Prall, Friedrich
RA   Linnebacher, Michael
RT   "Integrated biobanking and tumor model establishment of human
RT   colorectal carcinoma provides excellent tools for preclinical
RT   research.";
RL   Cancers (Basel) 11:1520.1-1520.18(2019).
//
RX   PubMed=25574089; DOI=10.3748/wjg.v21.i1.164; PMCID=PMC4284332;
RA   Maletzki, Claudia
RA   Gock, Michael
RA   Randow, Martin
RA   Klar, Ernst
RA   Huhns, Maja
RA   Prall, Friedrich
RA   Linnebacher, Michael
RT   "Establishment and characterization of cell lines from chromosomal
RT   instable colorectal cancer.";
RL   World J. Gastroenterol. 21:164-176(2015).
//