Cellosaurus cell line AIK-T4 (CVCL

Cellosaurus AIK-T4 (CVCL_1B42)

Cross-references
Cell line name	AIK-T4
Accession	CVCL_1B42
Resource Identification Initiative	To cite this cell line use: AIK-T4 (RRID:CVCL_1B42)
Comments	Virology: Contains an EBV genome in an episomal form (PubMed=8608235). Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV). Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178. Cell type: T-cell; CL=CL_0000084.
Sequence variations	Mutation; HGNC; HGNC:882; ATR; Unexplicit; Ex18del; Zygosity=Heterozygous (PubMed=16827800).
Disease	Severe chronic active EBV infection (NCIt: C162687)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual	CVCL_1B43 ! AIK-T8
Sex of cell	Female
Age at sampling	9Y
Category	Transformed cell line
Publications	PubMed=8608235; DOI=10.1182/blood.V87.4.1446.bloodjournal8741446 Imai S., Sugiura M., Oikawa O., Koizumi S., Hirao M., Kimura H., Hayashibara H., Terai N., Tsutsumi H., Oda T., Chiba S., Osato T. Epstein-Barr virus (EBV)-carrying and -expressing T-cell lines established from severe chronic active EBV infection. Blood 87:1446-1457(1996) PubMed=16827800; DOI=10.1111/j.1349-7006.2006.00226.x; PMCID=PMC11159954 Liu A., Takakuwa T., Luo W.-J., Fujita S., Aozasa K. Alterations in ATR in nasal NK/T-cell lymphoma and chronic active Epstein-Barr virus infection. Cancer Sci. 97:605-610(2006)
Chemistry resources	ChEMBL-Cells; CHEMBL3307276 ChEMBL-Targets; CHEMBL614024 PubChem_Cell_line; CVCL_1B42
Encyclopedic resources	Wikidata; Q54748994
Entry history
Entry creation	08-Jul-2015
Last entry update	19-Dec-2024
Version number	6