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Cellosaurus Ben-Men-1 (CVCL_1959)

[Text version]
Cell line name Ben-Men-1
Synonyms BEN-MEN-1; BenMen 1; Benign-Meningioma-1
Accession CVCL_1959
Resource Identification Initiative To cite this cell line use: Ben-Men-1 (RRID:CVCL_1959)
Comments Doubling time: 25.6 hours (PubMed=15965488); ~40-50 hours (DSMZ=ACC-599).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Omics: Deep exome analysis.
Derived from site: In situ; Brain, falx cerebri; UBERON=UBERON_0006059.
Sequence variations
Disease Meningothelial meningioma (NCIt: C4329)
Meningioma (ORDO: Orphanet_2495)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_JK01 (Ben-Men-1-LucB)
Sex of cell Female
Age at sampling 68Y
Category Telomerase immortalized cell line
STR profile Source(s): DSMZ=ACC-599

Markers:
AmelogeninX
CSF1PO10,11
D2S133820,25
D3S135816
D5S81812,13
D7S8209
D8S117911,12
D13S31711,12
D16S53913
D18S5114,17
D19S43314,15
D21S1129,32.2
FGA21,22
Penta D10,11
Penta E10,11
TH019
TPOX8,11
vWA14,18

Run an STR similarity search on this cell line
Publications

PubMed=15965488; DOI=10.1038/labinvest.3700307
Puttmann S., Senner V., Braune S., Hillmann B., Exeler R., Rickert C.H., Paulus W.
Establishment of a benign meningioma cell line by hTERT-mediated immortalization.
Lab. Invest. 85:1163-1171(2005)

PubMed=23151902; DOI=10.1158/0008-5472.CAN-12-1888; PMCID=PMC3549000
Burns S.S., Akhmametyeva E.M., Oblinger J.L., Bush M.L., Huang J., Senner V., Chen C.-S., Jacob A., Welling D.B., Chang L.-S.
Histone deacetylase inhibitor AR-42 differentially affects cell-cycle transit in meningeal and meningioma cells, potently inhibiting NF2-deficient meningioma growth.
Cancer Res. 73:792-803(2013)

PubMed=28552950; DOI=10.1371/journal.pone.0178322; PMCID=PMC5446134
Mei Y., Bi W.-Y.L., Greenwald N.F., Agar N.Y.R., Beroukhim R., Dunn G.P., Dunn I.F.
Genomic profile of human meningioma cell lines.
PLoS ONE 12:E0178322-E0178322(2017)

Cross-references
Cell line collections (Providers) DSMZ; ACC-599
Cell line databases/resources DSMZCellDive; ACC-599
Anatomy/cell type resources BTO; BTO_0004399
Biological sample resources BioSample; SAMN03473495
Encyclopedic resources Wikidata; Q54795998
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number25