ID   L-132
AC   CVCL_1908
SY   L132; L 132
DR   CLO; CLO_0007140
DR   CLO; CLO_0007158
DR   CLO; CLO_0007159
DR   CLDB; cl3076
DR   CLDB; cl3077
DR   CLDB; cl3078
DR   ATCC; CCL-5
DR   BCRJ; 0139
DR   BioSample; SAMN03151735
DR   ChEMBL-Cells; CHEMBL3307504
DR   ChEMBL-Targets; CHEMBL613999
DR   ECACC; 89111004
DR   IZSLER; BS CL 55
DR   JCRB; NIHS0050
DR   KCLB; 10005
DR   PubChem_Cell_line; CVCL_1908
DR   Wikidata; Q54900860
RX   CelloPub=CLPUB00071;
RX   DOI=10.1007/BF02618370;
RX   DOI=10.2198/sbk.34.289;
RX   PubMed=566722;
RX   PubMed=1246601;
RX   PubMed=5641128;
RX   PubMed=14185313;
RX   PubMed=20143388;
RX   PubMed=23925245;
WW   https://iclac.org/wp-content/uploads/Cross-Contaminations_v12_distribution.xlsx
CC   Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=5641128; PubMed=566722; PubMed=1246601; PubMed=20143388). Originally thought to be a lung embryonic cell line.
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00025.
CC   Population: African American.
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Omics: Genome sequenced (low read coverage).
CC   Discontinued: JCRB; NIHS0050; true.
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
ST   Source(s): ATCC; ECACC; KCLB
ST   Amelogenin: X
ST   CSF1PO: 9,10
ST   D13S317: 12,13.3 (ATCC; KCLB)
ST   D13S317: 12,14 (ECACC)
ST   D16S539: 9,10
ST   D3S1358: 15,18
ST   D5S818: 11,12
ST   D7S820: 8,12
ST   FGA: 18,21
ST   TH01: 7
ST   TPOX: 8,12
ST   vWA: 16,18
DI   NCIt; C27677; Human papillomavirus-related cervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0030 ! HeLa
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 27
//
RX   CelloPub=CLPUB00071;
RA   Davis E.V., Bolin V.S.;
RT   "Continuous cultivation of isogenous cell lines from the human
RT   embryo.";
RL   Fed. Proc. 19:386-386(1960).
//
RX   DOI=10.1007/BF02618370;
RA   Stulberg C.S., Coriell L.L., Kniazeff A.J., Shannon J.E.;
RT   "The animal cell culture collection.";
RL   In Vitro 5:1-16(1970).
//
RX   DOI=10.2198/sbk.34.289;
RA   Mizusawa H.;
RT   "Operation of the JCRB cell bank and isoenzyme.";
RL   Seibutsu Butsuri Kagaku 34:289-292(1990).
//
RX   PubMed=566722; DOI=10.1007/BF02616110;
RA   Lavappa K.S.;
RT   "Survey of ATCC stocks of human cell lines for HeLa contamination.";
RL   In Vitro 14:469-475(1978).
//
RX   PubMed=1246601; DOI=10.1126/science.1246601;
RA   Nelson-Rees W.A., Flandermeyer R.R.;
RT   "HeLa cultures defined.";
RL   Science 191:96-98(1976).
//
RX   PubMed=5641128; DOI=10.1038/217750a0;
RA   Gartler S.M.;
RT   "Apparent Hela cell contamination of human heteroploid cell lines.";
RL   Nature 217:750-751(1968).
//
RX   PubMed=14185313; DOI=10.1126/science.146.3641.241;
RG   Cell Culture Collection Committee;
RT   "Animal cell strains. The Cell Culture Collection Committee has
RT   assembled and certified 23 strains of animal cells.";
RL   Science 146:241-243(1964).
//
RX   PubMed=20143388; DOI=10.1002/ijc.25242;
RA   Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A.,
RA   MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R.,
RA   Freshney R.I.;
RT   "Check your cultures! A list of cross-contaminated or misidentified
RT   cell lines.";
RL   Int. J. Cancer 127:1-8(2010).
//
RX   PubMed=23925245; DOI=10.1038/nature12064;
RA   Adey A., Burton J.N., Kitzman J.O., Hiatt J.B., Lewis A.P.,
RA   Martin B.K., Qiu R.-L., Lee C., Shendure J.;
RT   "The haplotype-resolved genome and epigenome of the aneuploid HeLa
RT   cancer cell line.";
RL   Nature 500:207-211(2013).
//