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Cellosaurus U-2973 (CVCL_1898)

[Text version]
Cell line name U-2973
Accession CVCL_1898
Resource Identification Initiative To cite this cell line use: U-2973 (RRID:CVCL_1898)
Comments Doubling time: ~35 hours (DSMZ=ACC-642).
Omics: Genome sequenced.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
Disease High grade B-cell lymphoma with MYC and BCL2 or BCL6 rearrangements (NCIt: C125904)
High grade B-cell lymphoma with MYC and/or BCL2 and/or BCL6 rearrangement (ORDO: Orphanet_480541)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 42Y
Category Cancer cell line
STR profile Source(s): DSMZ=ACC-642

Markers:
AmelogeninX,Y
CSF1PO11
D2S133823,24
D3S135815,18
D5S81811,12
D7S82010,11
D8S117913
D13S31710,11
D16S53911,13
D18S5112,16
D19S43313,14
D21S1129,32.2
FGA21,22
Penta D12,13
Penta E16
TH017,9.3
TPOX8
vWA17,20

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Publications

PubMed=18510704; DOI=10.1111/j.1600-0609.2008.01098.x
Bostrom H., Leuchowius K.-J., Hallbook H., Nordgren A., Thorn I., Thorselius M., Rosenquist R., Soderberg O., Sundstrom C.
U-2973, a novel B-cell line established from a patient with a mature B-cell leukemia displaying concurrent t(14;18) and MYC translocation to a non-IG gene partner.
Eur. J. Haematol. 81:218-225(2008)

PubMed=23171647; DOI=10.1186/1756-0500-5-648; PMCID=PMC3534606
Hooper S.D., Jiao X., Sundstrom E., Rehman F.L., Tellgren-Roth C., Sjoblom T., Cavelier L.
Sequence based analysis of U-2973, a cell line established from a double-hit B-cell lymphoma with concurrent MYC and BCL2 rearrangements.
BMC Res. Notes 5:648.1-648.4(2012)

PubMed=26727417; DOI=10.3109/10428194.2015.1108414
Drexler H.G., Eberth S., Nagel S., MacLeod R.A.F.
Malignant hematopoietic cell lines: in vitro models for double-hit B-cell lymphomas.
Leuk. Lymphoma 57:1015-1020(2016)

Cross-references
Cell line collections (Providers) DSMZ; ACC-642
Cell line databases/resources DSMZCellDive; ACC-642
Biological sample resources BioSample; SAMN03473456
Chemistry resources ChEMBL-Cells; CHEMBL4523524
ChEMBL-Targets; CHEMBL4523555
PubChem_Cell_line; CVCL_1898
Encyclopedic resources Wikidata; Q54973563
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number23