ID   TMM
AC   CVCL_1894
DR   CLO; CLO_0009376
DR   CLDB; cl4533
DR   BioSample; SAMN03151631
DR   BioSample; SAMN03473406
DR   DSMZ; ACC-95
DR   DSMZCellDive; ACC-95
DR   Wikidata; Q54972699
RX   PubMed=3478106;
RX   PubMed=10516762;
RX   PubMed=20143388;
RX   PubMed=20454443;
WW   https://iclac.org/wp-content/uploads/Cross-Contaminations_v12_distribution.xlsx
CC   Problematic cell line: Misclassified. Originally thought to be a leukemia cell line from a patient with myelodysplastic syndrome but is a B-lymphoblastoid cell line (PubMed=10516762; PubMed=20143388).
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00279.
CC   Doubling time: ~20-40 hours (DSMZ=ACC-95).
CC   Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
ST   Source(s): DSMZ
ST   Amelogenin: X,Y
ST   CSF1PO: 10,11
ST   D13S317: 12,14
ST   D16S539: 10,12
ST   D18S51: 13,16
ST   D19S433: 14,15
ST   D21S11: 29,32.2
ST   D2S1338: 18,19
ST   D3S1358: 15,18
ST   D5S818: 11
ST   D7S820: 10,11
ST   D8S1179: 11,13
ST   FGA: 17.3,23
ST   Penta D: 11,12
ST   Penta E: 7
ST   TH01: 8,9.3
ST   TPOX: 8,9
ST   vWA: 14,18
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   62Y
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 21-03-23; Version: 19
//
RX   PubMed=3478106; DOI=10.1182/blood.V70.5.1665.1665;
RA   McCarty T.M., Rajaraman S., Elder F.F.B., Gadson P., Thompson E.B.;
RT   "Establishment and characterization of a human myeloid cell line from
RT   Philadelphia chromosome-negative myeloblastic leukemia arising in a
RT   patient with myelodysplastic syndrome.";
RL   Blood 70:1665-1672(1987).
//
RX   PubMed=10516762; DOI=10.1038/sj.leu.2401510;
RA   Drexler H.G., Dirks W.G., MacLeod R.A.F.;
RT   "False human hematopoietic cell lines: cross-contaminations and
RT   misinterpretations.";
RL   Leukemia 13:1601-1607(1999).
//
RX   PubMed=20143388; DOI=10.1002/ijc.25242;
RA   Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A.,
RA   MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R.,
RA   Freshney R.I.;
RT   "Check your cultures! A list of cross-contaminated or misidentified
RT   cell lines.";
RL   Int. J. Cancer 127:1-8(2010).
//
RX   PubMed=20454443; DOI=10.1155/2010/904767;
RA   Uphoff C.C., Denkmann S.A., Steube K.G., Drexler H.G.;
RT   "Detection of EBV, HBV, HCV, HIV-1, HTLV-I and -II, and SMRV in human
RT   and other primate cell lines.";
RL   J. Biomed. Biotechnol. 2010:904767.1-904767.23(2010).
//