ID   CCRF-SB
AC   CVCL_1860
SY   CCRF SB; CCRFSB; SB; S.B.; GM04154; GM04154B
DR   CLO; CLO_0002336
DR   CLO; CLO_0016198
DR   EFO; EFO_0006550
DR   CLDB; cl679
DR   CLDB; cl680
DR   CLDB; cl681
DR   ArrayExpress; E-MTAB-2706
DR   ATCC; CCL-120
DR   BioSample; SAMN03471043
DR   BioSample; SAMN03472769
DR   cancercelllines; CVCL_1860
DR   CCRID; 4201HUM-CCTCC00304
DR   CCTCC; GDC0304
DR   ChEMBL-Cells; CHEMBL3307643
DR   ChEMBL-Targets; CHEMBL614542
DR   Coriell; GM04154
DR   Cosmic; 683533
DR   Cosmic; 2301562
DR   Cosmic; 2649231
DR   ECACC; 89090405
DR   EGA; EGAS00001000610
DR   GEO; GSM5137709
DR   IARC_TP53; 21219
DR   IGRhCellID; CCRFSB
DR   IZSLER; BS TCL 12
DR   JCRB; IFO50026
DR   JCRB; JCRB0032
DR   LINCS_LDP; LCL-1006
DR   NCI-DTP; CCRF-SB
DR   PharmacoDB; CCRFSB_191_2019
DR   PRIDE; PXD023662
DR   Progenetix; CVCL_1860
DR   PubChem_Cell_line; CVCL_1860
DR   Wikidata; Q54809040
RX   CelloPub=CLPUB00447;
RX   DOI=10.1007/BF02618370;
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RX   PubMed=62390;
RX   PubMed=1086134;
RX   PubMed=3335022;
RX   PubMed=4363409;
RX   PubMed=4523807;
RX   PubMed=4991454;
RX   PubMed=8316623;
RX   PubMed=20215515;
RX   PubMed=25485619;
RX   PubMed=25877200;
RX   PubMed=26589293;
RX   PubMed=29892436;
RX   PubMed=35124168;
RX   PubMed=35354797;
CC   Population: Caucasian.
CC   HLA typing: A*01:01,02:01; B*44:05,57:01; C*02:02,06:02 (PubMed=26589293).
CC   Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
CC   Omics: Proteomics; Quantitative.
CC   Omics: Transcriptomics; RNAseq.
CC   Omics: Variations; SNP array analysis.
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
CC   Cell type: B-cell; CL=CL_0000236.
ST   Source(s): ATCC=CCL-120; JCRB=IFO50026; JCRB=JCRB0032; PubMed=25877200
ST   Amelogenin: X,Y
ST   CSF1PO: 10,12
ST   D13S317: 10,12
ST   D16S539: 9,13 (ATCC=CCL-120; PubMed=25877200)
ST   D16S539: 13 (JCRB=IFO50026; JCRB=JCRB0032)
ST   D18S51: 9,14
ST   D19S433: 14,16
ST   D21S11: 27,28
ST   D2S1338: 17,18
ST   D3S1358: 16,17
ST   D5S818: 11,12
ST   D7S820: 11,12
ST   D8S1179: 9,15
ST   FGA: 25
ST   Penta D: 9,12
ST   Penta E: 6,13
ST   TH01: 9,10
ST   TPOX: 8
ST   vWA: 18
DI   NCIt; C7953; Childhood T acute lymphoblastic leukemia
DI   ORDO; Orphanet_99861; Precursor T-cell acute lymphoblastic leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_1859 ! CCRF-HSB-2
SX   Male
AG   11Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 34
//
RX   PubMed=25877200; DOI=10.1038/nature14397;
RA   Yu, Ma-Mie
RA   Selvaraj, Suresh K.
RA   Liang-Chu, May M.Y.
RA   Aghajani, Sahar
RA   Busse, Matthew
RA   Yuan, Jean
RA   Lee, Genee
RA   Peale, Franklin V.
RA   Klijn, Christiaan
RA   Bourgon, Richard
RA   Kaminker, Joshua S.
RA   Neve, Richard M.
RT   "A resource for cell line authentication, annotation and quality
RT   control.";
RL   Nature 520:307-311(2015).
//
RX   PubMed=25485619; DOI=10.1038/nbt.3080;
RA   Klijn, Christiaan
RA   Durinck, Steffen
RA   Stawiski, Eric W.
RA   Haverty, Peter M.
RA   Jiang, Zhao-Shi
RA   Liu, Han-Bin
RA   Degenhardt, Jeremiah
RA   Mayba, Oleg
RA   Gnad, Florian
RA   Liu, Jin-Feng
RA   Pau, Gregoire
RA   Reeder, Jens
RA   Cao, Yi
RA   Mukhyala, Kiran
RA   Selvaraj, Suresh K.
RA   Yu, Ma-Mie
RA   Zynda, Gregory J.
RA   Brauer, Matthew J.
RA   Wu, Thomas D.
RA   Gentleman, Robert Clifford
RA   Manning, Gerard
RA   Yauch, Robert L.
RA   Bourgon, Richard
RA   Stokoe, David
RA   Modrusan, Zora
RA   Neve, Richard M.
RA   de Sauvage, Frederic J.
RA   Settleman, Jeffrey
RA   Seshagiri, Somasekar
RA   Zhang, Ze-Min
RT   "A comprehensive transcriptional portrait of human cancer cell
RT   lines.";
RL   Nat. Biotechnol. 33:306-312(2015).
//
RX   PubMed=35124168; DOI=10.1016/j.jsbmb.2022.106068;
RA   Tamai, Minori
RA   Kasai, Shin
RA   Akahane, Koshi
RA   Thu, Thao Nguyen
RA   Kagami, Keiko
RA   Komatsu, Chiaki
RA   Abe, Masako
RA   Watanabe, Atsushi
RA   Goi, Kumiko
RA   Miyake, Kunio
RA   Inaba, Toshiya
RA   Takita, Junko
RA   Goto, Hiroaki
RA   Minegishi, Masayoshi
RA   Iwamoto, Shotaro
RA   Sugita, Kanji
RA   Inukai, Takeshi
RT   "Glucocorticoid receptor gene mutations confer glucocorticoid
RT   resistance in B-cell precursor acute lymphoblastic leukemia.";
RL   J. Steroid Biochem. Mol. Biol. 218:106068.1-106068.12(2022).
//
RX   PubMed=4363409; DOI=10.1084/jem.139.5.1070; PMCID=PMC2139653;
RA   Kaplan, Joseph
RA   Shope, Thomas C.
RA   Peterson, Ward Davis Jr.
RT   "Epstein-Barr virus-negative human malignant T-cell lines.";
RL   J. Exp. Med. 139:1070-1076(1974).
//
RX   PubMed=62390; DOI=10.1111/j.1365-3083.1976.tb03029.x;
RA   Yount, William J.
RA   Utsinger, Peter D.
RA   Hutt-Fletcher, Lindsey M.
RA   Buchanan, Philip D.
RA   Korn, Joseph H.
RA   Fuller, C. Randall
RA   Logue, Marshall J.
RA   Pagano, Joseph S.
RT   "Subpopulations of human lymphoblastoid cell lines. Correlation with
RT   the expression of surface receptors and content of Epstein-Barr virus
RT   genome.";
RL   Scand. J. Immunol. 5:795-810(1976).
//
RX   PubMed=4523807; DOI=10.1007/BF02616012;
RA   Lazarus, Herbert
RA   Barell, Elizabeth Ferguson
RA   Oppenheim, Selma O.
RA   Krishan, Awtar
RT   "Divergent properties of two human lymphocytic cell lines isolated
RT   from a single specimen of peripheral blood.";
RL   In Vitro 9:303-310(1974).
//
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RA   Drexler, Hans Gunther
RT   "The leukemia-lymphoma cell line factsbook.";
RL   (In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001).
//
RX   PubMed=4991454; DOI=10.1016/0014-4827(79)90504-4;
RA   Adams, Richard A.
RA   Pothier, Lillian
RA   Flowers, Arlene
RA   Lazarus, Herbert
RA   Farber, Sidney
RA   Foley, George E.
RT   "The question of stemlines in human acute leukemia. Comparison of
RT   cells isolated in vitro and in vivo from a patient with acute
RT   lymphoblastic leukemia.";
RL   Exp. Cell Res. 62:5-10(1970).
//
RX   PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878;
RA   Scholtalbers, Jelle
RA   Boegel, Sebastian
RA   Bukur, Thomas
RA   Byl, Marius
RA   Goerges, Sebastian
RA   Sorn, Patrick
RA   Loewer, Martin
RA   Sahin, Ugur
RA   Castle, John C.
RT   "TCLP: an online cancer cell line catalogue integrating HLA type,
RT   predicted neo-epitopes, virus and gene expression.";
RL   Genome Med. 7:118.1-118.7(2015).
//
RX   DOI=10.1007/BF02618370;
RA   Stulberg, Cyril S.
RA   Coriell, Lewis Lemon
RA   Kniazeff, Alexis John
RA   Shannon, John E.
RT   "The animal cell culture collection.";
RL   In Vitro 5:1-16(1970).
//
RX   CelloPub=CLPUB00447;
RA   Mulivor, Richard A.
RA   Suchy, Sharon F.
RT   "1992/1993 catalog of cell lines. NIGMS human genetic mutant cell
RT   repository. 16th edition. October 1992.";
RL   (In misc. document) Institute for Medical Research (Camden, N.J.) NIH 92-2011; pp.1-918; National Institutes of Health; Bethesda; USA (1992).
//
RX   PubMed=3335022;
RA   Alley, Michael Curtis
RA   Scudiero, Dominic A.
RA   Monks, Anne
RA   Hursey, Miriam L.
RA   Czerwinski, Maciej J.
RA   Fine, Donald L.
RA   Abbott, Betty Jane
RA   Mayo, Joseph G.
RA   Shoemaker, Robert H.
RA   Boyd, Michael R.
RT   "Feasibility of drug screening with panels of human tumor cell lines
RT   using a microculture tetrazolium assay.";
RL   Cancer Res. 48:589-601(1988).
//
RX   PubMed=29892436; DOI=10.1098/rsos.172472; PMCID=PMC5990783;
RA   Shioda, Setsuko
RA   Kasai, Fumio
RA   Watanabe, Ken
RA   Kawakami, Kohei
RA   Ohtani, Azusa
RA   Iemura, Masashi
RA   Ozawa, Midori
RA   Arakawa, Akemi
RA   Hirayama, Noriko
RA   Kawaguchi, Eiko
RA   Tano, Tomoko
RA   Miyata, Sayaka
RA   Satoh, Motonobu
RA   Shimizu, Norio
RA   Kohara, Arihiro
RT   "Screening for 15 pathogenic viruses in human cell lines registered at
RT   the JCRB Cell Bank: characterization of in vitro human cells by viral
RT   infection.";
RL   R. Soc. Open Sci. 5:172472-172472(2018).
//
RX   PubMed=8316623; DOI=10.2307/3578190;
RA   Evans, Helen Harrington
RA   Ricanati, Marlene
RA   Horng, Min-Fen
RA   Jiang, Qiao-Yun
RA   Mencl, Jaroslav
RA   Olive, Peggy Louise
RT   "DNA double-strand break rejoining deficiency in TK6 and other human
RT   B-lymphoblast cell lines.";
RL   Radiat. Res. 134:307-315(1993).
//
RX   PubMed=35354797; DOI=10.1038/s41467-022-29224-5; PMCID=PMC8967900;
RA   Leo, Isabelle Rose
RA   Aswad, Luay
RA   Stahl, Matthias
RA   Kunold, Elena
RA   Post, Frederik
RA   Erkers, Tom
RA   Struyf, Nona
RA   Mermelekas, Georgios
RA   Joshi, Rubin Narayan
RA   Gracia-Villacampa, Eva
RA   Ostling, Paivi
RA   Kallioniemi, Olli-Pekka
RA   Pokrovskaja Tamm, Katja
RA   Siavelis, Ioannis
RA   Lehtio, Janne
RA   Vesterlund, Mattias
RA   Jafari, Rozbeh
RT   "Integrative multi-omics and drug response profiling of childhood
RT   acute lymphoblastic leukemia cell lines.";
RL   Nat. Commun. 13:1691.1-1691.19(2022).
//
RX   PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662;
RA   Rothenberg, S. Michael
RA   Mohapatra, Gayatry
RA   Rivera, Miguel N.
RA   Winokur, Daniel
RA   Greninger, Patricia
RA   Nitta, Mai
RA   Sadow, Peter M.
RA   Sooriyakumar, Gaya
RA   Brannigan, Brian W.
RA   Ulman, Matthew J.
RA   Perera, Rushika M.
RA   Wang, Rui
RA   Tam, Angela
RA   Ma, Xiao-Jun
RA   Erlander, Mark
RA   Sgroi, Dennis C.
RA   Rocco, James W.
RA   Lingen, Mark W.
RA   Cohen, Ezra E.W.
RA   Louis, David Neil
RA   Settleman, Jeffrey
RA   Haber, Daniel Arie
RT   "A genome-wide screen for microdeletions reveals disruption of
RT   polarity complex genes in diverse human cancers.";
RL   Cancer Res. 70:2158-2164(2010).
//
RX   PubMed=1086134;
RA   Kaplan, Joseph
RA   Peterson, Ward Davis Jr.
RT   "Detection of T-cell lymphoma-associated antigens on cord blood
RT   lymphocytes and phytohemagglutinin-stimulated blasts.";
RL   Cancer Res. 36:3471-3475(1976).
//