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Cellosaurus PaCaDD-137 (CVCL_1850)

[Text version]
Cell line name PaCaDD-137
Synonyms PACADD-137; PACADD137
Accession CVCL_1850
Resource Identification Initiative To cite this cell line use: PaCaDD-137 (RRID:CVCL_1850)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Caucasian.
Doubling time: 24.24 hours (PubMed=21683373); ~2-3 days (DSMZ=ACC-711).
Omics: Deep exome analysis.
Derived from site: In situ; Pancreas, head; UBERON=UBERON_0001069.
Sequence variations
  • Mutation; HGNC; 1787; CDKN2A; Simple; p.Arg80Ter (c.237_238CC>TT) (c.237_238delinsTT) (p.Pro94Leu, c.280_281CC>TT); Zygosity=Homozygous (DepMap).
  • Mutation; HGNC; 9588; PTEN; Simple; p.Lys267Argfs*9 (c.800delA) (p.Leu265fs, c.795delA); ClinVar=VCV000092828; Zygosity=Heterozygous (DepMap).
Disease Pancreatic adenocarcinoma (NCIt: C8294)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 75Y
Category Cancer cell line
STR profile Source(s): DepMap; DSMZ

Markers:
AmelogeninX
CSF1PO11,12
D2S133818,19
D3S135815,16
D5S8189,12
D7S8209,10
D8S117910 (DSMZ)
10,12 (DepMap)
D13S31711
D16S53911,12
D18S5114
D19S43312,13
D21S1129.2,32.2
FGA25,26
Penta D9,11
Penta E12,17
TH019,9.3
TPOX8
vWA18,19 (DSMZ)
18,19,20 (DepMap)

Run an STR similarity search on this cell line
Publications

PubMed=21683373; DOI=10.1016/j.jss.2011.04.021
Ruckert F., Aust D., Bohme I., Werner K., Brandt A., Diamandis E.P., Krautz C., Hering S., Saeger H.-D., Grutzmann R., Pilarsky C.
Five primary human pancreatic adenocarcinoma cell lines established by the outgrowth method.
J. Surg. Res. 172:29-39(2012)

DOI=10.4172/2324-9293.1000104
Wagenhauser M.U., Ruckert F., Niedergethmann M., Grutzmann R., Saeger H.-D.
Distribution of characteristic mutations in native ductal adenocarcinoma of the pancreas and pancreatic cancer cell lines.
Cell Biol. Res. Ther. 2:1000104.1-1000104.5(2013)

Cross-references
Cell line collections (Providers) DSMZ; ACC-711
Cell line databases/resources cancercelllines; CVCL_1850
Cell_Model_Passport; SIDM01352
DepMap; ACH-001377
DSMZCellDive; ACC-711
Encyclopedic resources Wikidata; Q54937423
Polymorphism and mutation databases Cosmic; 1559066
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number20