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Cellosaurus PaCaDD-135 (CVCL_1849)

[Text version]
Cell line name PaCaDD-135
Synonyms PACADD-135; PACADD135
Accession CVCL_1849
Resource Identification Initiative To cite this cell line use: PaCaDD-135 (RRID:CVCL_1849)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Caucasian.
Doubling time: 43.83 hours (PubMed=21683373); ~72 hours (DSMZ=ACC-710).
Omics: Deep exome analysis.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000027.
Sequence variations
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Unspecified (PubMed=21683373; DepMap).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg249fs (c.746_750_delGGCCC); Zygosity=Unspecified (DepMap).
Disease Pancreatic adenocarcinoma (NCIt: C8294)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 48Y
Category Cancer cell line
STR profile Source(s): DepMap; DSMZ

Markers:
AmelogeninX
CSF1PO10
D2S133818,20
D3S135815,16
D5S81811,12
D7S82011,12
D8S117913
D13S31711,13
D16S53911,12
D18S5117
D19S43313,15
D21S1129
FGA19
Penta D2,12 (DSMZ)
12 (DepMap)
Penta E5,11
TH019,9.3
TPOX8,11
vWA14,19

Run an STR similarity search on this cell line
Publications

PubMed=21683373; DOI=10.1016/j.jss.2011.04.021
Ruckert F., Aust D., Bohme I., Werner K., Brandt A., Diamandis E.P., Krautz C., Hering S., Saeger H.-D., Grutzmann R., Pilarsky C.
Five primary human pancreatic adenocarcinoma cell lines established by the outgrowth method.
J. Surg. Res. 172:29-39(2012)

DOI=10.4172/2324-9293.1000104
Wagenhauser M.U., Ruckert F., Niedergethmann M., Grutzmann R., Saeger H.-D.
Distribution of characteristic mutations in native ductal adenocarcinoma of the pancreas and pancreatic cancer cell lines.
Cell Biol. Res. Ther. 2:1000104.1-1000104.5(2013)

Cross-references
Cell line collections (Providers) DSMZ; ACC-710
Cell line databases/resources cancercelllines; CVCL_1849
Cell_Model_Passport; SIDM01353
DepMap; ACH-001376
DSMZCellDive; ACC-710
Encyclopedic resources Wikidata; Q54937422
Polymorphism and mutation databases Cosmic; 1559064
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number21