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Cellosaurus PaCaDD-119 (CVCL_1848)

[Text version]
Cell line name PaCaDD-119
Synonyms PACADD-119; PACADD119
Accession CVCL_1848
Resource Identification Initiative To cite this cell line use: PaCaDD-119 (RRID:CVCL_1848)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Caucasian.
Doubling time: 47.45 hours (PubMed=21683373); ~3-4 days (DSMZ=ACC-709).
Omics: Deep exome analysis.
Derived from site: In situ; Pancreas, head; UBERON=UBERON_0001069.
Sequence variations
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Ala (c.35G>C); ClinVar=VCV000045122; Zygosity=Unspecified (PubMed=21683373; DepMap).
  • Mutation; HGNC; 11998; TP53; Simple; p.Cys238Tyr (c.713G>A); ClinVar=VCV000182935; Zygosity=Unspecified (DepMap).
Disease Pancreatic adenocarcinoma (NCIt: C8294)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 59Y
Category Cancer cell line
STR profile Source(s): DepMap; DSMZ

Markers:
AmelogeninX
CSF1PO12
D2S133817,25
D3S135815,17
D5S81812,13
D7S82010,12
D8S117910
D13S31713
D16S5399,12
D18S5116
D19S43313,14
D21S1128
FGA21,22
Penta D10
Penta E9,12
TH017
TPOX8
vWA17

Run an STR similarity search on this cell line
Publications

PubMed=21683373; DOI=10.1016/j.jss.2011.04.021
Ruckert F., Aust D., Bohme I., Werner K., Brandt A., Diamandis E.P., Krautz C., Hering S., Saeger H.-D., Grutzmann R., Pilarsky C.
Five primary human pancreatic adenocarcinoma cell lines established by the outgrowth method.
J. Surg. Res. 172:29-39(2012)

DOI=10.4172/2324-9293.1000104
Wagenhauser M.U., Ruckert F., Niedergethmann M., Grutzmann R., Saeger H.-D.
Distribution of characteristic mutations in native ductal adenocarcinoma of the pancreas and pancreatic cancer cell lines.
Cell Biol. Res. Ther. 2:1000104.1-1000104.5(2013)

Cross-references
Cell line collections (Providers) DSMZ; ACC-709
Cell line databases/resources cancercelllines; CVCL_1848
Cell_Model_Passport; SIDM01354
DepMap; ACH-001375
DSMZCellDive; ACC-709
Encyclopedic resources Wikidata; Q54937421
Polymorphism and mutation databases Cosmic; 1559062
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number22