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Cellosaurus TE 381.T (CVCL_1751)

[Text version]
Cell line name TE 381.T
Synonyms TE-381-T; TE381T; RD114-B
Accession CVCL_1751
Resource Identification Initiative To cite this cell line use: TE 381.T (RRID:CVCL_1751)
Comments Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).
Population: Caucasian.
Characteristics: Established through passage of the parent cell line in a fetal cat (ATCC=CRL-7763).
Omics: SNP array analysis.
Caution: Wrongly indicated by ATCC to originate from a 7 week old female donor. Older product sheets of ATCC correctly indicated it originates from a 7 year old female.
Derived from site: In situ; Pelvis, muscle; UBERON=UBERON_0001325.
Sequence variations
  • Mutation; HGNC; 7989; NRAS; Simple; p.Gln61His (c.183A>T); ClinVar=VCV000373003; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg248Trp (c.742C>T); ClinVar=VCV000012347; Zygosity=Homozygous (from parent cell line).
Disease Embryonal rhabdomyosarcoma (NCIt: C8971)
Embryonal rhabdomyosarcoma (ORDO: Orphanet_99757)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1649 (RD)
Sex of cell Female
Age at sampling 7Y
Category Cancer cell line
STR profile Source(s): ATCC

Markers:
AmelogeninX
CSF1PO10,11
D5S81811
D7S8208,12
D13S31713
D16S53910,11
TH019.3
TPOX9
vWA18

Run an STR similarity search on this cell line
Publications

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

Cross-references
Cell line collections (Providers) ATCC; CRL-7763
Cell line databases/resources CLO; CLO_0009300
cancercelllines; CVCL_1751
IGRhCellID; TE381T
Encyclopedic resources Wikidata; Q54971966
Gene expression databases ArrayExpress; E-MTAB-38
Polymorphism and mutation databases Cosmic; 1309332
Progenetix; CVCL_1751
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number15