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Cellosaurus TE 125.T (CVCL_1740)

[Text version]
Cell line name TE 125.T
Synonyms TE-125-T; TE125T
Accession CVCL_1740
Resource Identification Initiative To cite this cell line use: TE 125.T (RRID:CVCL_1740)
Comments Problematic cell line: Misclassified. Originally thought to be a rhabdomyosarcoma cell line but using a variety of omics methods was shown to be a a fibroblastic cell line (DOI=10.1101/166199; DepMap=ACH-000079).
Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).
Omics: Deep exome analysis.
Omics: Transcriptome analysis by RNAseq.
Cell type: Fibroblast; CL=CL_0000057.
HLA typing Source: PubMed=26589293
Class I
HLA-AA*02:06,11:01
HLA-BB*35:21,51:01
HLA-CC*04:01,15:09
Class II
HLA-DQDQA1*01:02,01:02
HLA-DRDRB1*13:02,15:66
Genome ancestry Source: PubMed=30894373

Origin% genome
African5.57
Native American41.29
East Asian, North1.9
East Asian, South0.18
South Asian0
European, North25.13
European, South25.92
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 1Y
Category Undefined cell line type
Publications

PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878
Scholtalbers J., Boegel S., Bukur T., Byl M., Goerges S., Sorn P., Loewer M., Sahin U., Castle J.C.
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Genome Med. 7:118.1-118.7(2015)

DOI=10.1101/166199
de Weck A., Bitter H., Kauffmann A.
Fibroblasts cell lines misclassified as cancer cell lines.
bioRxiv 2017:166199-166199(2017)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. 3rd, Barretina J.G., Gelfand E.T., Bielski C.M., Li H.-X., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y.-L., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cross-references
Cell line collections (Providers) ATCC; CRL-7945 - Discontinued
ATCC; CRL-7945_FL - Discontinued
Cell line databases/resources CLO; CLO_0009289
cancercelllines; CVCL_1740
Cell_Model_Passport; SIDM01763
DepMap; ACH-000079
Biological sample resources BioSample; SAMN10988446
Chemistry resources PharmacoDB; TE125_T_1571_2019
Encyclopedic resources Wikidata; Q54971943
Gene expression databases ArrayExpress; E-MTAB-2770
Polymorphism and mutation databases LiGeA; CCLE_274
Progenetix; CVCL_1740
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number23