Cellosaurus cell line SBC-7 [Human contaminated bladder carcinoma] (CVCL

Cellosaurus SBC-7 [Human contaminated bladder carcinoma] (CVCL_1680)

[Text version]

Cell line name

SBC-7 [Human contaminated bladder carcinoma]

Synonyms

SBC7

Accession

CVCL_1680

Resource Identification Initiative

To cite this cell line use: SBC-7 [Human contaminated bladder carcinoma] (RRID:CVCL_1680)

Comments

Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=10508494; PubMed=20143388). Originally thought to originate from an urinary bladder carcinoma.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00157.
Population: African American.
Doubling time: ~15-17 hours (DSMZ=ACC-229).
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.

Disease

Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Parent: CVCL_0030 (HeLa)

Sex of cell

Female

Age at sampling

30Y6M

Category

Cancer cell line

STR profile

Source(s): DSMZ=ACC-229

Markers:

Amelogenin	X
CSF1PO	9,10
D2S1338	17
D3S1358	15,18
D5S818	11,12
D7S820	12
D8S1179	12
D13S317	12,13.3
D16S539	9,10
D18S51	16
D19S433	13,14
D21S11	27,28
FGA	21
Penta D	8,15
Penta E	7,17
TH01	7
TPOX	8,12
vWA	16,18

Web pages

https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx

Publications

PubMed=8230540; DOI=10.1016/S0022-5347(17)35941-4
Bohle A., Thanhauser A., Ulmer A.J., Ernst M., Flad H.-D., Jocham D.
Dissecting the immunobiological effects of Bacillus Calmette-Guerin (BCG) in vitro: evidence of a distinct BCG-activated killer (BAK) cell phenomenon.
J. Urol. 150:1932-1937(1993)

PubMed=10508494; DOI=10.1002/(SICI)1097-0215(19991112)83:4<555::AID-IJC19>3.0.CO;2-2
MacLeod R.A.F., Dirks W.G., Matsuo Y., Kaufmann M., Milch H., Drexler H.G.
Widespread intraspecies cross-contamination of human tumor cell lines arising at source.
Int. J. Cancer 83:555-563(1999)

PubMed=11668190; DOI=10.1177/002215540104901105
Quentmeier H., Osborn M., Reinhardt J., Zaborski M., Drexler H.G.
Immunocytochemical analysis of cell lines derived from solid tumors.
J. Histochem. Cytochem. 49:1369-1378(2001)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Cross-references

Cell line collections (Providers)

DSMZ; ACC-229 - Discontinued

Cell line databases/resources

CLO; CLO_0008952
CLDB; cl4258
DSMZCellDive; ACC-229

Biological sample resources

BioSample; SAMN03151756

Encyclopedic resources

Wikidata; Q54952183

Entry history

Entry creation

04-Apr-2012

Last entry update

02-May-2024

Version number