ID   RF-48
AC   CVCL_1657
SY   RF48
DR   CLO; CLO_0037147
DR   ArrayExpress; E-MTAB-783
DR   ArrayExpress; E-MTAB-3610
DR   ATCC; CRL-1863
DR   BioSample; SAMN03471256
DR   cancercelllines; CVCL_1657
DR   Cell_Model_Passport; SIDM01092
DR   Cosmic; 909697
DR   Cosmic-CLP; 909697
DR   DepMap; ACH-002301
DR   EGA; EGAS00001000978
DR   GDSC; 909697
DR   GEO; GSM1670375
DR   IARC_TP53; 21286
DR   IZSLER; BS TCL 208
DR   LINCS_LDP; LCL-1896
DR   PharmacoDB; RF48_1309_2019
DR   PRIDE; PXD030304
DR   Wikidata; Q54949801
RX   PubMed=7750094;
RX   PubMed=12226758;
RX   PubMed=20164919;
RX   PubMed=27397505;
RX   PubMed=30894373;
RX   PubMed=35839778;
CC   Problematic cell line: Misclassified. From a B-cell lymphoma and not from the ascites of a gastric adenocarcinoma (PubMed=12226758).
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Part of: COSMIC cell lines project.
CC   Microsatellite instability: Stable (MSS) (Sanger).
CC   Omics: Deep exome analysis.
CC   Omics: Deep quantitative proteome analysis.
CC   Omics: DNA methylation analysis.
CC   Omics: SNP array analysis.
CC   Omics: Transcriptome analysis by microarray.
CC   Genome ancestry: African=5.29%; Native American=31.68%; East Asian, North=3.25%; East Asian, South=0%; South Asian=2.87%; European, North=27.68%; European, South=29.24% (PubMed=30894373).
CC   Discontinued: ATCC; CRL-1863; true.
ST   Source(s): ATCC; Cosmic-CLP
ST   Amelogenin: X,Y
ST   CSF1PO: 11
ST   D13S317: 12
ST   D16S539: 11,13
ST   D5S818: 11,12
ST   D7S820: 10,12
ST   TH01: 7,8
ST   TPOX: 8,12
ST   vWA: 15,16
DI   NCIt; C3208; Lymphoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_3580 ! RF-1
SX   Male
AG   62Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 29
//
RX   PubMed=7750094; DOI=10.1016/0304-3835(95)03717-b;
RA   Salesiotis A.N., Wang C.K., Wang C.D., Burger A., Li H., Seth A.;
RT   "Identification of novel genes from stomach cancer cell lines by
RT   differential display.";
RL   Cancer Lett. 91:47-54(1995).
//
RX   PubMed=12226758; DOI=10.1038/sj.onc.1205829;
RA   Ji J.-F., Chen X., Leung S.Y., Chi J.-T.A., Chu K.M., Yuen S.T., Li R.,
RA   Chan A.S.Y., Li J.-Y., Dunphy N., So S.;
RT   "Comprehensive analysis of the gene expression profiles in human
RT   gastric cancer cell lines.";
RL   Oncogene 21:6549-6556(2002).
//
RX   PubMed=20164919; DOI=10.1038/nature08768;
RA   Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S.,
RA   Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S.,
RA   Hinton J., Fahey C., Fu B.-Y., Swamy S., Dalgliesh G.L., Teh B.T.,
RA   Deloukas P., Yang F.-T., Campbell P.J., Futreal P.A., Stratton M.R.;
RT   "Signatures of mutation and selection in the cancer genome.";
RL   Nature 463:893-898(2010).
//
RX   PubMed=27397505; DOI=10.1016/j.cell.2016.06.017;
RA   Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P.,
RA   Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H.,
RA   Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H.,
RA   Deng X.-M., Egan R.K., Liu Q.-S., Mironenko T., Mitropoulos X.,
RA   Richardson L., Wang J.-H., Zhang T.-H., Moran S., Sayols S.,
RA   Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P.,
RA   Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H.,
RA   Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.;
RT   "A landscape of pharmacogenomic interactions in cancer.";
RL   Cell 166:740-754(2016).
//
RX   PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747;
RA   Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.;
RT   "An interactive resource to probe genetic diversity and estimated
RT   ancestry in cancer cell lines.";
RL   Cancer Res. 79:1263-1273(2019).
//
RX   PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010;
RA   Goncalves E., Poulos R.C., Cai Z.-X., Barthorpe S., Manda S.S., Lucas N.,
RA   Beck A., Bucio-Noble D., Dausmann M., Hall C., Hecker M., Koh J.,
RA   Lightfoot H., Mahboob S., Mali I., Morris J., Richardson L.,
RA   Seneviratne A.J., Shepherd R., Sykes E., Thomas F., Valentini S.,
RA   Williams S.G., Wu Y.-X., Xavier D., MacKenzie K.L., Hains P.G., Tully B.,
RA   Robinson P.J., Zhong Q., Garnett M.J., Reddel R.R.;
RT   "Pan-cancer proteomic map of 949 human cell lines.";
RL   Cancer Cell 40:835-849.e8(2022).
//