Cellosaurus OC 316 (CVCL_1618)
Cell line name | OC 316 | ||||||||||||||||
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Synonyms | OC-316; OC316 | ||||||||||||||||
Accession | CVCL_1618 | ||||||||||||||||
Resource Identification Initiative | To cite this cell line use: OC 316 (RRID:CVCL_1618) | ||||||||||||||||
Comments | Problematic cell line: Contaminated. Identical to OC 314 according to STR profiling done at ICLC, to MSI data (PubMed=15677628) and to omic data (DepMap). Originally thought to originate from a 60 year old patient with a FIGO stage IV ovarian cancer. Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). Part of: MD Anderson Cell Lines Project. Population: Caucasian. Microsatellite instability: Instable (MSI-high) (PubMed=15677628; PubMed=31068700). Omics: Deep exome analysis. Omics: Protein expression by reverse-phase protein arrays. Omics: SNP array analysis. Omics: Transcriptome analysis by microarray. Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795. | ||||||||||||||||
Sequence variations |
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Genome ancestry | Source: PubMed=30894373
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Disease | Ovarian serous adenocarcinoma (NCIt: C7550) | ||||||||||||||||
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) | ||||||||||||||||
Hierarchy | Parent: CVCL_1616 (OC 314) | ||||||||||||||||
Sex of cell | Female | ||||||||||||||||
Age at sampling | 39Y | ||||||||||||||||
Category | Cancer cell line | ||||||||||||||||
Web pages | https://tcpaportal.org/mclp/ | ||||||||||||||||
Publications | PubMed=8690298; DOI=10.1006/gyno.1996.0194 PubMed=15677628; DOI=10.1093/carcin/bgi032 PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027 PubMed=23415752; DOI=10.1016/j.molonc.2012.12.007; PMCID=PMC4106023 PubMed=23839242; DOI=10.1038/ncomms3126; PMCID=PMC3715866 PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076 PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675 PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103 | ||||||||||||||||
Cross-references | |||||||||||||||||
Cell line collections (Providers) | ICLC; HTL98014 - Discontinued | ||||||||||||||||
Cell line databases/resources | CLO; CLO_0008233
cancercelllines; CVCL_1618 Cell_Model_Passport; SIDM00219 DepMap; ACH-001145 | ||||||||||||||||
Anatomy/cell type resources | BTO; BTO:0006437 | ||||||||||||||||
Biological sample resources | BioSample; SAMN10987675 | ||||||||||||||||
Chemistry resources | PharmacoDB; OC316_1181_2019 | ||||||||||||||||
Encyclopedic resources | Wikidata; Q54931703 | ||||||||||||||||
Gene expression databases | GEO; GSM887467
GEO; GSM888547 | ||||||||||||||||
Polymorphism and mutation databases | IARC_TP53; 21597
Progenetix; CVCL_1618 | ||||||||||||||||
Entry history | |||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||
Last entry update | 02-May-2024 | ||||||||||||||||
Version number | 26 |