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Cellosaurus OC 315 (CVCL_1617)

[Text version]
Cell line name OC 315
Synonyms OC-315; OC315
Accession CVCL_1617
Resource Identification Initiative To cite this cell line use: OC 315 (RRID:CVCL_1617)
Comments Problematic cell line: Possibly contaminated. May be identical to OC 314 (Cellosaurus=CVCL_1616) according to STR profiling done at ICLC and to MSI data (PubMed=15677628).
Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Microsatellite instability: Instable (MSI-high) (PubMed=15677628).
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Disease Ovarian serous adenocarcinoma (NCIt: C7550)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 49Y
Category Cancer cell line

PubMed=8690298; DOI=10.1006/gyno.1996.0194
Alama A., Barbieri F., Favre A., Cagnoli M., Noviello E., Pedulla F., Viale M., Foglia G., Ragni N.
Establishment and characterization of three new cell lines derived from the ascites of human ovarian carcinomas.
Gynecol. Oncol. 62:82-88(1996)

PubMed=15677628; DOI=10.1093/carcin/bgi032
Gorringe K.L., Chin S.-F., Pharoah P.D.P., Staines J.M., Oliveira C., Edwards P.A.W., Caldas C.
Evidence that both genetic instability and selection contribute to the accumulation of chromosome alterations in cancer.
Carcinogenesis 26:923-930(2005)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J.G., Gelfand E.T., Bielski C.M., Li H.-X., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y.-L., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cell line collections (Providers) ICLC; HTL98013 - Discontinued
Cell line databases/resources CLO; CLO_0008232
cancercelllines; CVCL_1617
Cell_Model_Passport; SIDM01823
DepMap; ACH-001144
Anatomy/cell type resources BTO; BTO:0006436
Chemistry resources PharmacoDB; OC315_1180_2019
Encyclopedic resources Wikidata; Q54931702
Gene expression databases GEO; GSM459737
Polymorphism and mutation databases Progenetix; CVCL_1617
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number20