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Cellosaurus NCI-H2330 (CVCL_1548)

[Text version]
Cell line name NCI-H2330
Synonyms H2330; H-2330
Accession CVCL_1548
Resource Identification Initiative To cite this cell line use: NCI-H2330 (RRID:CVCL_1548)
Comments Population: Caucasian.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Donor information: Established from a 65 packs per year smoker (ATCC=CRL-5940).
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Disease Lung small cell carcinoma (NCIt: C4917)
Small cell lung cancer (ORDO: Orphanet_70573)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 57Y
Category Cancer cell line
STR profile Source(s): ATCC=CRL-5940

Markers:
AmelogeninX
CSF1PO10
D2S133817,25
D3S135814
D5S81812
D7S8209,10
D8S117912
D13S3179
D16S53911,12
D18S5112,17
D19S43313,14
D21S1130,31
FGA22
Penta D8,9
Penta E17
TH019.3
TPOX8
vWA18,19

Run an STR similarity search on this cell line
Publications

PubMed=8806092; DOI=10.1002/jcb.240630505
Phelps R.M., Johnson B.E., Ihde D.C., Gazdar A.F., Carbone D.P., McClintock P.R., Linnoila R.I., Matthews M.J., Bunn P.A. Jr., Carney D.N., Minna J.D., Mulshine J.L.
NCI-Navy Medical Oncology Branch cell line data base.
J. Cell. Biochem. Suppl. 24:32-91(1996)

PubMed=8806103; DOI=10.1002/jcb.240630516
Johnson B.E., Russell E., Simmons A.M., Phelps R.M., Steinberg S.M., Ihde D.C., Gazdar A.F.
MYC family DNA amplification in 126 tumor cell lines from patients with small cell lung cancer.
J. Cell. Biochem. Suppl. 24:210-217(1996)

PubMed=11030152; DOI=10.1038/sj.onc.1203815
Modi S., Kubo A., Oie H.K., Coxon A.B., Rehmatulla A., Kaye F.J.
Protein expression of the RB-related gene family and SV40 large T antigen in mesothelioma and lung cancer.
Oncogene 19:4632-4639(2000)

PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113
Bignell G.R., Greenman C.D., Davies H.R., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B.-Y., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F.-T., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

PubMed=31803961; DOI=10.1002/jcb.29564; PMCID=PMC7496084
Mulshine J.L., Ujhazy P., Antman M., Burgess C.M., Kuzmin I.A., Bunn P.A. Jr., Johnson B.E., Roth J.A., Pass H.I., Ross S.M., Aldige C.R., Wistuba I.I., Minna J.D.
From clinical specimens to human cancer preclinical models -- a journey the NCI-cell line database-25 years later.
J. Cell. Biochem. 121:3986-3999(2020)

Cross-references
Cell line collections (Providers) ATCC; CRL-5940
Cell line databases/resources CLO; CLO_0008072
cancercelllines; CVCL_1548
Biological sample resources BioSample; SAMN03472606
Encyclopedic resources Wikidata; Q54907963
Gene expression databases ArrayExpress; E-MTAB-783
GEO; GSM827444
Polymorphism and mutation databases Cosmic; 688019
Progenetix; CVCL_1548
Entry history
Entry creation04-Apr-2012
Last entry update10-Sep-2024
Version number24