Cellosaurus Mo (CVCL_1439)
Cell line name | Mo | ||||||||||||||||||||||||||||||||||||
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Synonyms | MO; Mo-T; Mo T; MoT; MOT | ||||||||||||||||||||||||||||||||||||
Accession | CVCL_1439 | ||||||||||||||||||||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: Mo (RRID:CVCL_1439) | ||||||||||||||||||||||||||||||||||||
Comments | Group: Patented cell line. Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). Part of: COSMIC cell lines project. Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-8066. Population: Caucasian. Microsatellite instability: Stable (MSS) (Sanger). Transformant: NCBI_TaxID; 11909; Human T-lymphotropic virus 2 (HTLV-2). Omics: Deep exome analysis. Omics: Deep quantitative proteome analysis. Omics: DNA methylation analysis. Omics: Transcriptome analysis by microarray. Anecdotal: John Moore, the patient from which this cell line is derived, sued David Golde and the University of California over the patent that they deposited on the Mo cell line. Although his claims of ownership were rejected, his physician was deemed to have breached his fiduciary duty by not informing Moore of the economic and financial interests arising from the derivation of the cell line. Derived from site: In situ; Spleen; UBERON=UBERON_0002106. Cell type: T-cell; CL=CL_0000084. | ||||||||||||||||||||||||||||||||||||
Genome ancestry | Source: PubMed=30894373
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Disease | Hairy cell leukemia (NCIt: C7402) Classic hairy cell leukemia (ORDO: Orphanet_58017) | ||||||||||||||||||||||||||||||||||||
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) | ||||||||||||||||||||||||||||||||||||
Originate from same individual | CVCL_2302 ! Mo-B | ||||||||||||||||||||||||||||||||||||
Sex of cell | Male | ||||||||||||||||||||||||||||||||||||
Age at sampling | 33Y | ||||||||||||||||||||||||||||||||||||
Category | Cancer cell line | ||||||||||||||||||||||||||||||||||||
STR profile | Source(s): ATCC=CRL-8066; Cosmic-CLP=908149 Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||||||||||||||||||||
Web pages | https://en.wikipedia.org/wiki/Moore_v._Regents_of_the_University_of_California https://scocal.stanford.edu/opinion/moore-v-regents-university-california-31115 http://www.bio.davidson.edu/people/kabernd/Indep/carainbow/Cells.htm http://www.wipo.int/wipo_magazine/en/2006/05/article_0008.html http://helatermproject.blogspot.ch/2012/03/john-moore.html | ||||||||||||||||||||||||||||||||||||
Publications | PubMed=305224; DOI=10.7326/0003-4819-88-3-323 PubMed=6984393 PubMed=6987658; DOI=10.1073/pnas.77.1.593; PMCID=PMC348320 PubMed=6981847; DOI=10.1126/science.6981847 PubMed=6600440; DOI=10.1007/BF02617996 Patent=US4438032 CLPUB00468 PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469 PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675 PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775 | ||||||||||||||||||||||||||||||||||||
Cross-references | |||||||||||||||||||||||||||||||||||||
Cell line collections (Providers) | ATCC; CRL-8066 | ||||||||||||||||||||||||||||||||||||
Cell line databases/resources | CLO; CLO_0007815
CLO; CLO_0037184 cancercelllines; CVCL_1439 Cell_Model_Passport; SIDM00623 Cosmic-CLP; 908149 DepMap; ACH-002339 LINCS_LDP; LCL-1096 Lonza; 1308 | ||||||||||||||||||||||||||||||||||||
Anatomy/cell type resources | BTO; BTO:0001014 | ||||||||||||||||||||||||||||||||||||
Biological sample resources | BioSample; SAMN03471131 | ||||||||||||||||||||||||||||||||||||
Chemistry resources | ChEMBL-Cells; CHEMBL3308631
ChEMBL-Targets; CHEMBL614722 GDSC; 908149 PharmacoDB; MoT_947_2019 PubChem_Cell_line; CVCL_1439 | ||||||||||||||||||||||||||||||||||||
Encyclopedic resources | Wikidata; Q54906275 | ||||||||||||||||||||||||||||||||||||
Gene expression databases | ArrayExpress; E-MTAB-3610
GEO; GSM1670121 GEO; GSM1670131 | ||||||||||||||||||||||||||||||||||||
Polymorphism and mutation databases | Cosmic; 683660
Cosmic; 908149 Cosmic; 1120712 IARC_TP53; 21525 | ||||||||||||||||||||||||||||||||||||
Proteomic databases | PRIDE; PXD030304 | ||||||||||||||||||||||||||||||||||||
Sequence databases | EGA; EGAS00001000978 | ||||||||||||||||||||||||||||||||||||
Entry history | |||||||||||||||||||||||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||||||||||||||||||||||
Last entry update | 02-May-2024 | ||||||||||||||||||||||||||||||||||||
Version number | 36 |