Cellosaurus MRK-nu-1 (CVCL_1428)
Cell line name | MRK-nu-1 | ||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Synonyms | MRK-NU-1; MRK-nu-I; Mrk-nu1; MRKnu-1; MRKnu1; MRKNU1 | ||||||||||||||||||
Accession | CVCL_1428 | ||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: MRK-nu-1 (RRID:CVCL_1428) | ||||||||||||||||||
Comments | Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). Part of: COSMIC cell lines project. Population: Japanese. Characteristics: Established from the ascitic cells from BALB/c nu/nu mice injected intraperitoneal with the parent tumoral cells. Doubling time: ~47 hours (Note=Lot 02072012) (JCRB=JCRB0628). Microsatellite instability: Stable (MSS) (Sanger). Omics: Deep exome analysis. Omics: Deep quantitative proteome analysis. Omics: DNA methylation analysis. Omics: SNP array analysis. Omics: Transcriptome analysis by microarray. Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175. | ||||||||||||||||||
Sequence variations |
| ||||||||||||||||||
Genome ancestry | Source: PubMed=30894373
| ||||||||||||||||||
Disease | Breast carcinoma (NCIt: C4872) | ||||||||||||||||||
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) | ||||||||||||||||||
Originate from same individual | CVCL_WZ71 ! MRK-nu-2 | ||||||||||||||||||
Sex of cell | Female | ||||||||||||||||||
Age at sampling | 46Y | ||||||||||||||||||
Category | Cancer cell line | ||||||||||||||||||
STR profile | Source(s): Cosmic-CLP=908151; JCRB=JCRB0628 Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||
Publications | CLPUB00083 PubMed=518958 PubMed=9290701; DOI=10.1002/(SICI)1098-2744(199708)19:4<243::AID-MC5>3.0.CO;2-D PubMed=15900046; DOI=10.1093/jnci/dji133 PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113 PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662 PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469 PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675 PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775 | ||||||||||||||||||
Cross-references | |||||||||||||||||||
Cell line collections (Providers) | JCRB; JCRB0616 - Discontinued
JCRB; JCRB0628 | ||||||||||||||||||
Cell line databases/resources | CLO; CLO_0009914
cancercelllines; CVCL_1428 Cell_Model_Passport; SIDM00562 Cosmic-CLP; 908151 DepMap; ACH-002163 LINCS_LDP; LCL-1487 | ||||||||||||||||||
Anatomy/cell type resources | BTO; BTO_0003679 | ||||||||||||||||||
Biological sample resources | BioSample; SAMN03471641 | ||||||||||||||||||
Chemistry resources | ChEMBL-Cells; CHEMBL3308550
ChEMBL-Targets; CHEMBL2366325 GDSC; 908151 PharmacoDB; MRKnu1_965_2019 PubChem_Cell_line; CVCL_1428 | ||||||||||||||||||
Encyclopedic resources | Wikidata; Q54906738 | ||||||||||||||||||
Gene expression databases | ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-3610 GEO; GSM827236 GEO; GSM1670133 | ||||||||||||||||||
Polymorphism and mutation databases | Cosmic; 908151
IARC_TP53; 21516 Progenetix; CVCL_1428 | ||||||||||||||||||
Proteomic databases | PRIDE; PXD030304 | ||||||||||||||||||
Sequence databases | EGA; EGAS00001000978 | ||||||||||||||||||
Entry history | |||||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||||
Last entry update | 19-Dec-2024 | ||||||||||||||||||
Version number | 37 |