| Comments |
Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: COSMIC cell lines project.
Population: Japanese.
Doubling time: 49 hours (PubMed=9378542).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Array-based CGH.
Omics: Deep exome analysis.
Omics: Deep quantitative proteome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray. |
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| Genome ancestry |
Source: PubMed=30894373
| Origin | % genome |
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|
| African | 0.86 | | Native American | 0.24 | | East Asian, North | 77.99 | | East Asian, South | 19.62 | | South Asian | 1.28 | | European, North | 0 | | European, South | 0 |
|
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| Disease |
Neuroblastoma (NCIt: C3270)
Neuroblastoma (ORDO: Orphanet_635) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Sex of cell |
Female |
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| Age at sampling |
1Y8M |
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| Category |
Cancer cell line |
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| STR profile |
Source(s): Cosmic-CLP=1240181; JCRB=JCRB0154; PubMed=25877200
Markers:| Amelogenin | X |
| CSF1PO | 10,12 |
| D2S1338 | 17,19 |
| D3S1358 | 15 |
| D5S818 | 10 |
| D7S820 | 12 |
| D8S1179 | 13,16 |
| D13S317 | 12 |
| D16S539 | 9,11 (PubMed=25877200)
9,11,12 (Cosmic-CLP=1240181)
9,12 (JCRB=JCRB0154) |
| D18S51 | 13,15 |
| D19S433 | 13.2,14 |
| D21S11 | 30 |
| FGA | 22,24 |
| Penta D | 12,14 |
| Penta E | 14,19 |
| TH01 | 9 |
| TPOX | 11 |
| vWA | 14 |
Run an STR similarity search on this cell line |
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| Publications |
hybrid mapping panel for human chromosome 3.
Genomics 24:549-556(1994)
New immortalized human stromal cell lines enhancing in vitro expansion of cord blood hematopoietic stem cells.
Int. J. Mol. Med. 13:363-371(2004)
Elia G., Marincola F.M., McCubrey J.A., Libra M., Travali S., Kane M.
Characterization of human melanoma cell lines and melanocytes by proteome analysis.
Cell Cycle 10:2924-2936(2011)
Robison R.A., O'Neill K.L.
Non-small-cell lung cancer cell lines A549 and NCI-H460 express hypoxanthine guanine phosphoribosyltransferase on the plasma membrane.
Onco Targets Ther. 10:1921-1932(2017)
Cancer Sci. 109:3171-3182(2018)
Morelli E., Waszyk P., Kumar S., Deming D., Moret N., Rodriguez S., Subramanian K., Rogava M., Cartwright A.N.R., Luoma A., Mei S.-L., Brinker T.J., Miller D.M., Spektor A., Schadendorf D., Riggi N., Wucherpfennig K.W., Sorger P.K., Izar B.
Inhibition of haspin kinase promotes cell-intrinsic and extrinsic antitumor activity.
Cancer Res. 80:798-810(2020)
Correction to: Aurora B kinase as a therapeutic target in acute lymphoblastic leukemia.
Cancer Chemother. Pharmacol. 88:1055-1056(2021)
|
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| Cross-references |
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| Cell line collections (Providers) |
JCRB; JCRB0154
JCRB; NIHS0179 - Discontinued
|
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| Cell line databases/resources |
Cosmic-CLP; 1240181
DepMap; ACH-002277
LINCS_LDP; LCL-1976
|
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| Chemistry resources |
GDSC; 1240181
PharmacoDB; NBTU110_982_2019
|
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| Encyclopedic resources |
Wikidata; Q54907513
|
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| Gene expression databases |
GEO; GSM827250
GEO; GSM1670144
|
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| Polymorphism and mutation databases |
Cosmic; 2131596
Progenetix; CVCL_3041
|
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| Proteomic databases |
PRIDE; PXD030304
|
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| Sequence databases |
EGA; EGAS00001000978
|
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| Entry history |
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| Entry creation | 04-Apr-2012 |
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| Last entry update | 02-May-2024 |
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| Version number | 29 |
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