Cellosaurus K5 (CVCL_1322)
Cell line name | K5 | ||||||||||||||||||
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Accession | CVCL_1322 | ||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: K5 (RRID:CVCL_1322) | ||||||||||||||||||
Comments | Problematic cell line: Contaminated. Shown to be a GLAG-66 derivative (STR profile and somatic mutations from Cosmic-CLP). Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). Part of: COSMIC cell lines project. Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00590. Population: Caucasian; Italian. Microsatellite instability: Stable (MSS) (Sanger). Omics: Deep exome analysis. Omics: Deep quantitative proteome analysis. Omics: DNA methylation analysis. Omics: SNP array analysis. Omics: Transcriptome analysis by microarray. Derived from site: Metastatic; Thyroid gland; UBERON=UBERON_0002046. | ||||||||||||||||||
Sequence variations |
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Genome ancestry | Source: PubMed=30894373
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Disease | Thyroid gland papillary carcinoma (NCIt: C4035) Differentiated thyroid carcinoma (ORDO: Orphanet_146) | ||||||||||||||||||
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) | ||||||||||||||||||
Hierarchy | Parent: CVCL_9918 (GLAG-66) | ||||||||||||||||||
Sex of cell | Male | ||||||||||||||||||
Age at sampling | 58Y | ||||||||||||||||||
Category | Cancer cell line | ||||||||||||||||||
STR profile | Source(s): Cosmic-CLP=924238 Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||
Web pages | https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx | ||||||||||||||||||
Publications | PubMed=10646882; DOI=10.1054/bjoc.1999.0920; PMCID=PMC2363282 PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113 PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469 PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675 PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775 | ||||||||||||||||||
Cross-references | |||||||||||||||||||
Cell line databases/resources | CLO; CLO_0037154
cancercelllines; CVCL_1322 Cell_Model_Passport; SIDM00056 Cosmic-CLP; 924238 DepMap; ACH-002148 LINCS_LDP; LCL-1692 | ||||||||||||||||||
Chemistry resources | ChEMBL-Cells; CHEMBL3308144
ChEMBL-Targets; CHEMBL2366152 GDSC; 924238 PharmacoDB; K5_724_2019 PubChem_Cell_line; CVCL_1322 | ||||||||||||||||||
Encyclopedic resources | Wikidata; Q54899290 | ||||||||||||||||||
Gene expression databases | ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-3610 GEO; GSM1669970 | ||||||||||||||||||
Polymorphism and mutation databases | Cosmic; 924238
Cosmic; 928832 Cosmic; 1162843 Cosmic; 1507370 Cosmic; 1533547 Cosmic; 1536123 Cosmic; 1789444 Cosmic; 1889002 Cosmic; 2791090 IARC_TP53; 27559 | ||||||||||||||||||
Proteomic databases | PRIDE; PXD030304 | ||||||||||||||||||
Sequence databases | EGA; EGAS00001000978 | ||||||||||||||||||
Entry history | |||||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||||
Last entry update | 02-May-2024 | ||||||||||||||||||
Version number | 36 |