Cellosaurus HCE-4 (CVCL_1271)
Cell line name | HCE-4 | ||||||||||||||||||
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Synonyms | HCE4 | ||||||||||||||||||
Accession | CVCL_1271 | ||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: HCE-4 (RRID:CVCL_1271) | ||||||||||||||||||
Comments | Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). Part of: COSMIC cell lines project. Population: African American. Doubling time: 48 hours (PubMed=2415247). Microsatellite instability: Stable (MSS) (Sanger). Omics: CRISPR phenotypic screen. Omics: Deep exome analysis. Omics: Deep quantitative proteome analysis. Omics: DNA methylation analysis. Omics: SNP array analysis. Omics: Transcriptome analysis by microarray. Derived from site: In situ; Esophagus; UBERON=UBERON_0001043. | ||||||||||||||||||
Sequence variations |
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Genome ancestry | Source: PubMed=30894373
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Disease | Esophageal squamous cell carcinoma (NCIt: C4024) Squamous cell carcinoma of the esophagus (ORDO: Orphanet_99977) | ||||||||||||||||||
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) | ||||||||||||||||||
Originate from same individual | CVCL_5138 ! HCE-7 | ||||||||||||||||||
Sex of cell | Female | ||||||||||||||||||
Age at sampling | 50Y | ||||||||||||||||||
Category | Cancer cell line | ||||||||||||||||||
STR profile | Source(s): Cosmic-CLP=753559 Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||
Publications | PubMed=2415247 PubMed=2420787; DOI=10.1016/S0021-9258(17)38506-X PubMed=2263646; DOI=10.1073/pnas.87.24.9958; PMCID=PMC55293 PubMed=2302677; DOI=10.1016/0165-4608(90)90073-j PubMed=7972006; DOI=10.1073/pnas.91.23.11045; PMCID=PMC45163 PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113 PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469 PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675 PubMed=30971826; DOI=10.1038/s41586-019-1103-9 PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775 | ||||||||||||||||||
Cross-references | |||||||||||||||||||
Cell line databases/resources | CLO; CLO_0009932
cancercelllines; CVCL_1271 Cell_Model_Passport; SIDM00052 Cosmic-CLP; 753559 DepMap; ACH-002243 LINCS_LDP; LCL-1563 | ||||||||||||||||||
Anatomy/cell type resources | BTO; BTO_0005572 | ||||||||||||||||||
CRISP screens repositories | BioGRID_ORCS_Cell_line; 869 | ||||||||||||||||||
Chemistry resources | ChEMBL-Cells; CHEMBL3308199
ChEMBL-Targets; CHEMBL2366207 GDSC; 753559 PharmacoDB; HCE4_514_2019 PubChem_Cell_line; CVCL_1271 | ||||||||||||||||||
Encyclopedic resources | Wikidata; Q54881849 | ||||||||||||||||||
Gene expression databases | ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-3610 GEO; GSM482501 GEO; GSM1669865 | ||||||||||||||||||
Polymorphism and mutation databases | Cosmic; 753559
Cosmic; 923186 Cosmic; 934539 Cosmic; 1394519 IARC_TP53; 258 Progenetix; CVCL_1271 | ||||||||||||||||||
Proteomic databases | PRIDE; PXD030304 | ||||||||||||||||||
Sequence databases | EGA; EGAS00001000978 | ||||||||||||||||||
Entry history | |||||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||||
Last entry update | 19-Dec-2024 | ||||||||||||||||||
Version number | 37 |