ID   GA-10 clone 4
AC   CVCL_1224
SY   GA-10 (Clone 4); GA-10-Clone-4
DR   CLO; CLO_0003441
DR   ArrayExpress; E-MTAB-783
DR   ArrayExpress; E-MTAB-3610
DR   ATCC; CRL-2393
DR   cancercelllines; CVCL_1224
DR   Cell_Model_Passport; SIDM01252
DR   Cosmic; 687841
DR   Cosmic; 906867
DR   GEO; GSM1669802
DR   IARC_TP53; 21336
DR   PharmacoDB; GA10Clone4_396_2019
DR   Wikidata; Q54835417
RX   PubMed=11482875;
RX   PubMed=20164919;
CC   Population: Caucasian.
CC   Virology: EBV-negative.
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro152Leu (c.455C>T); ClinVar=VCV000142766; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ile232Asn (c.695T>A); ClinVar=VCV000850008; Zygosity=Heterozygous (from parent cell line).
CC   Omics: Genomics; DNA methylation analysis.
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Variations; SNP array analysis.
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
CC   Cell type: B-cell; CL=CL_0000236.
ST   Source(s): ATCC=CRL-2393
ST   Amelogenin: X,Y
ST   CSF1PO: 10
ST   D13S317: 11
ST   D16S539: 11,12
ST   D18S51: 14,18
ST   D19S433: 12,14
ST   D21S11: 28,30
ST   D2S1338: 20
ST   D3S1358: 18
ST   D5S818: 11
ST   D7S820: 8,10
ST   D8S1179: 11,13,14
ST   FGA: 20,23
ST   Penta D: 9,13
ST   Penta E: 5,12
ST   TH01: 9,9.3
ST   TPOX: 8,11
ST   vWA: 16,20
DI   NCIt; C7954; Adult Burkitt leukemia
DI   ORDO; Orphanet_543; Burkitt lymphoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1222 ! GA-10
SX   Male
AG   41Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 30
//
RX   PubMed=11482875; DOI=10.1006/bcmd.2001.0428;
RA   Rapoport, Aaron Paul
RA   Simons-Evelyn, Michelle
RA   Chen, Timothy
RA   Sidell, Rochel
RA   Luhowskyj, Shannon
RA   Rosell, Karen
RA   Obrig, Tom
RA   Hicks, David
RA   Hinkle, Patricia M.
RA   Nahm, Moon H.
RA   Insel, Richard A.
RA   Abboud, Camille N.
RT   "Flavopiridol induces apoptosis and caspase-3 activation of a newly
RT   characterized Burkitt's lymphoma cell line containing mutant p53
RT   genes.";
RL   Blood Cells Mol. Dis. 27:610-624(2001).
//
RX   PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113;
RA   Bignell, Graham Robert
RA   Greenman, Christopher D.
RA   Davies, Helen R.
RA   Butler, Adam P.
RA   Edkins, Sarah
RA   Andrews, Jenny M.
RA   Buck, Gemma
RA   Chen, Lina
RA   Beare, David
RA   Latimer, Calli
RA   Widaa, Sara
RA   Hinton, Jonathan
RA   Fahey, Ciara
RA   Fu, Bei-Yuan
RA   Swamy, Sajani
RA   Dalgliesh, Gillian L.
RA   Teh, Bin Tean
RA   Deloukas, Panos
RA   Yang, Feng-Tang
RA   Campbell, Peter J.
RA   Futreal, P. Andrew
RA   Stratton, Michael Rudolf
RT   "Signatures of mutation and selection in the cancer genome.";
RL   Nature 463:893-898(2010).
//