ID   D556 Med
AC   CVCL_1165
SY   D-556 Med; D-556MED; D-556Med; D556MED; D556Med; D-556; D556; H556
DR   ArrayExpress; E-MTAB-783
DR   cancercelllines; CVCL_1165
DR   Cell_Model_Passport; SIDM01821
DR   Cosmic; 946380
DR   Cosmic; 2362653
DR   DepMap; ACH-001055
DR   GEO; GSM482330
DR   GEO; GSM1234978
DR   GEO; GSM1234979
DR   IARC_TP53; 27692
DR   Progenetix; CVCL_1165
DR   Wikidata; Q54817246
RX   PubMed=9283596;
RX   PubMed=11916498;
RX   PubMed=16946619;
RX   PubMed=20164919;
RX   PubMed=20847082;
RX   PubMed=21177782;
RX   PubMed=24297863;
RX   PubMed=27498314;
RX   PubMed=27812533;
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Omics: SNP array analysis.
CC   Omics: Transcriptome analysis by microarray.
DI   NCIt; C129445; Medulloblastoma, non-WNT/non-SHH, group 3
DI   ORDO; Orphanet_616; Medulloblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   7Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 19
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RX   PubMed=9283596; DOI=10.1016/S0165-4608(96)00404-9;
RA   Bigner S.H., McLendon R.E., Fuchs H.E., McKeever P.E., Friedman H.S.;
RT   "Chromosomal characteristics of childhood brain tumors.";
RL   Cancer Genet. Cytogenet. 97:125-134(1997).
//
RX   PubMed=11916498; DOI=10.1093/neuonc/4.2.75;
RA   Aldosari N., Wiltshire R.N., Dutra A., Schrock E., McLendon R.E.,
RA   Friedman H.S., Bigner D.D., Bigner S.H.;
RT   "Comprehensive molecular cytogenetic investigation of chromosomal
RT   abnormalities in human medulloblastoma cell lines and xenograft.";
RL   Neuro-oncol. 4:75-85(2002).
//
RX   PubMed=16946619; DOI=10.1159/000095545;
RA   Dharmaraj P., Ball S., Johnstone H., Bailey S., Clifford S.C.,
RA   Hale J., Cheetham T.D.;
RT   "Hypercalcaemia in relapsed medulloblastoma 8 years post-diagnosis;
RT   evidence to support PTHrP production by medulloblastoma cells.";
RL   Horm. Res. 66:268-272(2006).
//
RX   PubMed=20164919; DOI=10.1038/nature08768;
RA   Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S.,
RA   Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S.,
RA   Hinton J., Fahey C., Fu B.-Y., Swamy S., Dalgliesh G.L., Teh B.T.,
RA   Deloukas P., Yang F.-T., Campbell P.J., Futreal P.A., Stratton M.R.;
RT   "Signatures of mutation and selection in the cancer genome.";
RL   Nature 463:893-898(2010).
//
RX   PubMed=20847082; DOI=10.1093/neuonc/noq091;
RA   Teider N., Scott D.K., Neiss A., Weeraratne S.D., Amani V.M., Wang Y.-F.,
RA   Marquez V.E., Cho Y.-J., Pomeroy S.L.;
RT   "Neuralized1 causes apoptosis and downregulates Notch target genes in
RT   medulloblastoma.";
RL   Neuro-oncol. 12:1244-1256(2010).
//
RX   PubMed=21177782; DOI=10.1093/neuonc/noq179;
RA   Weeraratne S.D., Amani V.M., Neiss A., Teider N., Scott D.K.,
RA   Pomeroy S.L., Cho Y.-J.;
RT   "miR-34a confers chemosensitivity through modulation of MAGE-A and p53
RT   in medulloblastoma.";
RL   Neuro-oncol. 13:165-175(2011).
//
RX   PubMed=24297863; DOI=10.1158/1078-0432.CCR-13-2281;
RA   Bandopadhayay P., Bergthold G., Nguyen B., Schubert S., Gholamin S.,
RA   Tang Y.-J., Bolin S., Schumacher S.E., Zeid R., Masoud S., Yu F.-R.,
RA   Vue N., Gibson W.J., Paolella B.R., Mitra S.S., Cheshier S.H., Qi J.,
RA   Liu K.-W., Wechsler-Reya R.J., Weiss W.A., Swartling F.J., Kieran M.W.,
RA   Bradner J.E., Beroukhim R., Cho Y.-J.;
RT   "BET bromodomain inhibition of MYC-amplified medulloblastoma.";
RL   Clin. Cancer Res. 20:912-925(2014).
//
RX   PubMed=27498314; DOI=10.1016/j.jbiotec.2016.07.028;
RA   Ivanov D.P., Coyle B., Walker D.A., Grabowska A.M.;
RT   "In vitro models of medulloblastoma: choosing the right tool for the
RT   job.";
RL   J. Biotechnol. 236:10-25(2016).
//
RX   PubMed=27812533; DOI=10.1016/j.dib.2016.10.004;
RA   Ivanov D.P., Walker D.A., Coyle B., Grabowska A.M.;
RT   "Data on the number and frequency of scientific literature citations
RT   for established medulloblastoma cell lines.";
RL   Data Brief 9:696-698(2016).
//