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Cellosaurus D384 Med (CVCL_1157)

[Text version]
Cell line name D384 Med
Synonyms D-384 Med; D-384 Med-C; D-384MED; D384Med; Med 384; H384
Accession CVCL_1157
Resource Identification Initiative To cite this cell line use: D384 Med (RRID:CVCL_1157)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Doubling time: 2.44 days (PubMed=1904513).
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Misspelling: D384MG; Cosmic=1175809.
Derived from site: In situ; Brain, cerebellum; UBERON=UBERON_0002037.
Disease Medulloblastoma, non-WNT/non-SHH, group 3 (NCIt: C129445)
Medulloblastoma (ORDO: Orphanet_616)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 1Y5M
Category Cancer cell line
Publications

PubMed=2180567
Bigner S.H., Friedman H.S., Vogelstein B., Oakes W.J., Bigner D.D.
Amplification of the c-myc gene in human medulloblastoma cell lines and xenografts.
Cancer Res. 50:2347-2350(1990)

PubMed=1822845
Wikstrand C.J., Friedman H.S., Bigner D.D.
Medulloblastoma cell-substrate interaction in vitro.
Invasion Metastasis 11:310-324(1991)

PubMed=1904513
He X.-M., Wikstrand C.J., Friedman H.S., Bigner S.H., Pleasure S., Trojanowski J.Q., Bigner D.D.
Differentiation characteristics of newly established medulloblastoma cell lines (D384 Med, D425 Med, and D458 Med) and their transplantable xenografts.
Lab. Invest. 64:833-843(1991)

DOI=10.1007/0-306-46861-1_11
Ali-Osman F.
Brain tumors.
(In) Human cell culture. Vol. 2. Cancer Cell Lines part 2; Masters J.R.W., Palsson B.O. (eds.); pp.167-184; Kluwer Academic Publishers; New York (1999)

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B.-Y., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F.-T., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=20847082; DOI=10.1093/neuonc/noq091
Teider N., Scott D.K., Neiss A., Weeraratne S.D., Amani V.M., Wang Y.-F., Marquez V.E., Cho Y.-J., Pomeroy S.L.
Neuralized1 causes apoptosis and downregulates Notch target genes in medulloblastoma.
Neuro-oncol. 12:1244-1256(2010)

PubMed=21177782; DOI=10.1093/neuonc/noq179
Weeraratne S.D., Amani V.M., Neiss A., Teider N., Scott D.K., Pomeroy S.L., Cho Y.-J.
miR-34a confers chemosensitivity through modulation of MAGE-A and p53 in medulloblastoma.
Neuro-oncol. 13:165-175(2011)

PubMed=27498314; DOI=10.1016/j.jbiotec.2016.07.028
Ivanov D.P., Coyle B., Walker D.A., Grabowska A.M.
In vitro models of medulloblastoma: choosing the right tool for the job.
J. Biotechnol. 236:10-25(2016)

PubMed=27812533; DOI=10.1016/j.dib.2016.10.004
Ivanov D.P., Walker D.A., Coyle B., Grabowska A.M.
Data on the number and frequency of scientific literature citations for established medulloblastoma cell lines.
Data Brief 9:696-698(2016)

Cross-references
Cell line databases/resources cancercelllines; CVCL_1157
Cell_Model_Passport; SIDM01856
DepMap; ACH-001052
Encyclopedic resources Wikidata; Q54817222
Gene expression databases ArrayExpress; E-MTAB-783
GEO; GSM482335
Polymorphism and mutation databases Cosmic; 946379
Cosmic; 1175809
IARC_TP53; 27690
Progenetix; CVCL_1157
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number22