ID   RPMI-4788
AC   CVCL_0U46
SY   RPMI 4788; RPMI4788; R.P.M.I. #4788; Roswell Park Memorial Institute 4788
DR   BioSample; SAMN03151753
DR   BioSample; SAMN03472398
DR   Wikidata; Q54951187
RX   PubMed=2504864;
RX   PubMed=14082866;
RX   PubMed=23136038;
CC   Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=23136038). Was originally thought to originate from the pleural fluid of a 73 year old female patient with a colon adenocarcinoma.
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00387.
CC   Population: African American.
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Discontinued: JCRB; JCRB1309; true.
CC   Discontinued: JCRB; NIHS0553; true.
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
ST   Source(s): JCRB
ST   Amelogenin: X
ST   CSF1PO: 9,10
ST   D13S317: 13.3
ST   D16S539: 10
ST   D5S818: 11,12
ST   D7S820: 8,12
ST   TH01: 7
ST   TPOX: 8,12
ST   vWA: 16,18
DI   NCIt; C27677; Human papillomavirus-related cervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0030 ! HeLa
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 08-07-15; Last updated: 05-10-23; Version: 15
RX   PubMed=2504864;
RA   Iwagaki H., Fuchimoto S., Shiiki S., Miyake M., Orita K.;
RT   "Monitoring the effect of an anti-cancer drug on RPMI 4788 cells by a
RT   membrane potential probe, dis-C3-(5).";
RL   J. Med. 20:135-141(1989).
RX   PubMed=14082866;
RA   Moore G.E., Mount D., Tara G., Schwartz N.;
RT   "Growth of human tumor cells in suspension cultures.";
RL   Cancer Res. 23:1735-1741(1963).
RX   PubMed=23136038; DOI=10.1002/ijc.27931;
RA   Capes-Davis A., Reid Y.A., Kline M.C., Storts D.R., Strauss E.,
RA   Dirks W.G., Drexler H.G., MacLeod R.A.F., Sykes G.R., Kohara A.,
RA   Nakamura Y., Elmore E., Nims R.W., Alston-Roberts C., Barallon R.,
RA   Los G.V., Nardone R.M., Price P.J., Steuer A., Thomson J.A.,
RA   Masters J.R.W., Kerrigan L.;
RT   "Match criteria for human cell line authentication: where do we draw
RT   the line?";
RL   Int. J. Cancer 132:2510-2519(2013).