ID   Panc1-bC2GnT-M
AC   CVCL_0Q69
DR   BTO; BTO:0005502
DR   cancercelllines; CVCL_0Q69
DR   Wikidata; Q54937556
RX   PubMed=10455130;
RX   PubMed=22525330;
CC   Population: Caucasian.
CC   Sequence variation: Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Homozygous (from parent cell line).
CC   Transfected with: HGNC; 7508; MUC1.
CC   Transfected with: VGNC; 56968; Bovine GCNT1.
CC   Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
DI   NCIt; C9120; Pancreatic ductal adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0Q68 ! Panc1-MUC1
SX   Male
AG   56Y
CA   Cancer cell line
DT   Created: 08-07-15; Last updated: 05-10-23; Version: 13
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RX   PubMed=10455130; DOI=10.1074/jbc.274.35.24641;
RA   Beum P.V., Singh J., Burdick M., Hollingsworth M.A., Cheng P.-W.;
RT   "Expression of core 2 beta-1,6-N-acetylglucosaminyltransferase in a
RT   human pancreatic cancer cell line results in altered expression of
RT   MUC1 tumor-associated epitopes.";
RL   J. Biol. Chem. 274:24641-24648(1999).
//
RX   PubMed=22525330; DOI=10.1016/j.biocel.2012.04.004;
RA   Petrosyan A., Ali M.F., Verma S.K., Cheng H., Cheng P.-W.;
RT   "Non-muscle myosin IIA transports a Golgi glycosyltransferase to the
RT   endoplasmic reticulum by binding to its cytoplasmic tail.";
RL   Int. J. Biochem. Cell Biol. 44:1153-1165(2012).
//