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Cellosaurus Panc1-MUC1 (CVCL_0Q68)

[Text version]
Cell line name Panc1-MUC1
Synonyms Panc1/MUC1
Accession CVCL_0Q68
Resource Identification Initiative To cite this cell line use: Panc1-MUC1 (RRID:CVCL_0Q68)
Comments Population: Caucasian.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:7508; MUC1.
Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Homozygous (from parent cell line).
Disease Pancreatic ductal adenocarcinoma (NCIt: C9120)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0480 (PANC-1)
Children:
CVCL_0Q69 (Panc1-bC2GnT-M)
Sex of cell Male
Age at sampling 56Y
Category Cancer cell line
Publications

PubMed=1814933; DOI=10.1242/jcs.100.4.841
Batra S.K., Kern H.F., Worlock A.J., Metzgar R.S., Hollingsworth M.A.
Transfection of the human Muc 1 mucin gene into a poorly differentiated human pancreatic tumor cell line, Panc1: integration, expression and ultrastructural changes.
J. Cell Sci. 100:841-849(1991)

Cross-references
Cell line databases/resources cancercelllines; CVCL_0Q68
Encyclopedic resources Wikidata; Q54937557
Entry history
Entry creation08-Jul-2015
Last entry update19-Dec-2024
Version number13