ID   BRITER
AC   CVCL_0P40
SY   BMP Responsive Immortalized reporTER cell line
DR   Kerafast; EBI001
DR   Wikidata; Q29957968
RX   PubMed=22611465;
CC   Characteristics: Responds robustly, promptly and specifically to exogenously added BMP2 protein.
CC   Characteristics: Transfected with a BRE-SV40minP-FFLuc-SV40P-HygR-IRES-RRLuc construct.
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Firefly luciferase.
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P27652; Renilla-type luciferase.
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Derived from site: In situ; Bone, calvaria; UBERON=UBERON_0004339.
CC   Cell type: Osteoblast; CL=CL_0000062.
CC   Breed/subspecies: Bmp2/4 dKO x R26CreER.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
CA   Transformed cell line
DT   Created: 10-04-15; Last updated: 10-09-24; Version: 11
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RX   PubMed=22611465; DOI=10.1371/journal.pone.0037134; PMCID=PMC3354957;
RA   Yadav P.S., Prashar P., Bandyopadhyay A.;
RT   "BRITER: a BMP responsive osteoblast reporter cell line.";
RL   PLoS ONE 7:E37134-E37134(2012).
//