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Cellosaurus 5H7 (CVCL_0P39)

[Text version]
Cell line name 5H7
Accession CVCL_0P39
Resource Identification Initiative To cite this cell line use: 5H7 (RRID:CVCL_0P39)
Comments Characteristics: Is diphtheria toxin (DT) resistant due to transfection with a DT-resistant elongation factor-2 (EEF2) gene.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:3214; EEF2 (Note=With p.Gly717Arg).
Genetic integration: Method=Transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA).
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0063 (HEK293T)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Publications

PubMed=20410930; DOI=10.1038/gt.2010.53; PMCID=PMC2910233
Wang Z.-R., Tang Z.-W., Zheng Y.-F., Yu D.-Y., Spear M., Iyer S.R., Bishop B., Wu Y.-T.
Development of a nonintegrating Rev-dependent lentiviral vector carrying diphtheria toxin A chain and human TRAF6 to target HIV reservoirs.
Gene Ther. 17:1063-1076(2010)

Cross-references
Cell line collections (Providers) Kerafast; EP0006 - Discontinued
Encyclopedic resources Wikidata; Q54604179
Entry history
Entry creation10-Apr-2015
Last entry update19-Dec-2024
Version number15