ID   DTC1
AC   CVCL_0J31
SY   DTC-1
DR   Wikidata; Q54831557
RX   PubMed=7753552;
RX   PubMed=12966428;
RX   PubMed=15150091;
RX   PubMed=16766266;
CC   Sequence variation: Gene fusion; HGNC; HGNC:783; ATF1 + HGNC; HGNC:3508; EWSR1; Name(s)=EWSR1-ATF1, EWS-ATF; Note=Type 1: EWSR1 exon 8 fused to ATF1 exon 4 (PubMed=7753552; PubMed=15150091).
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
DI   NCIt; C3745; Clear cell sarcoma of soft tissue
DI   ORDO; Orphanet_3394; Soft tissue sarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   Age unspecified
CA   Cancer cell line
DT   Created: 10-04-15; Last updated: 19-12-24; Version: 11
//
RX   PubMed=7753552;
RA   Brown A.D., Lopez-Terrada D.H., Denny C.T., Lee K.A.W.;
RT   "Promoters containing ATF-binding sites are de-regulated in cells that
RT   express the EWS/ATF1 oncogene.";
RL   Oncogene 10:1749-1756(1995).
//
RX   PubMed=12966428; DOI=10.1038/sj.bjc.6601212; PMCID=PMC2376962;
RA   Li K.K.C., Goodall J., Goding C.R., Liao S.-K., Wang C.-H., Lin Y.-C.,
RA   Hiraga H., Nojima T., Nagashima K., Schaefer K.-L., Lee K.A.W.;
RT   "The melanocyte inducing factor MITF is stably expressed in cell lines
RT   from human clear cell sarcoma.";
RL   Br. J. Cancer 89:1072-1078(2003).
//
RX   PubMed=15150091; DOI=10.1158/0008-5472.CAN-03-0809;
RA   Schaefer K.-L., Brachwitz K., Wai D.H., Braun Y., Diallo R.,
RA   Korsching E., Eisenacher M., Voss R., van Valen F., Baer C., Selle B.,
RA   Spahn L., Liao S.-K., Lee K.A.W., Hogendoorn P.C.W., Reifenberger G.,
RA   Gabbert H.E., Poremba C.;
RT   "Expression profiling of t(12;22) positive clear cell sarcoma of soft
RT   tissue cell lines reveals characteristic up-regulation of potential
RT   new marker genes including ERBB3.";
RL   Cancer Res. 64:3395-3405(2004).
//
RX   PubMed=16766266; DOI=10.1016/j.ccr.2006.04.021;
RA   Davis I.J., Kim J.J., Ozsolak F., Widlund H.R., Rozenblatt-Rosen O.,
RA   Granter S.R., Du J.-Y., Fletcher J.A., Denny C.T., Lessnick S.L.,
RA   Linehan W.M., Kung A.L.-J., Fisher D.E.;
RT   "Oncogenic MITF dysregulation in clear cell sarcoma: defining the MiT
RT   family of human cancers.";
RL   Cancer Cell 9:473-484(2006).
//