ID   HAPI
AC   CVCL_0F62
SY   Highly Aggressively Proliferating Immortalized
DR   BTO; BTO:0003618
DR   ATCC; CRL-2815
DR   Millipore; SCC103
DR   PRIDE; PXD000518
DR   Wikidata; Q54881308
RX   PubMed=11424192;
RX   PubMed=22121004;
RX   PubMed=22651808;
WW   https://iclac.org/wp-content/uploads/Cross-Contaminations_v12_distribution.xlsx
CC   Problematic cell line: Misidentified. Originally thought to be a microgial cell of rat origin (3 day old Wistar rat) but found to be from mouse (Millipore).
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00602.
CC   Omics: Deep proteome analysis.
CC   Misspelling: HAP1; Note=Occasionally.
CC   Discontinued: ATCC; CRL-2815; true.
CC   Discontinued: Millipore; SCC103; true.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
CA   Undefined cell line type
DT   Created: 10-04-15; Last updated: 21-03-23; Version: 14
//
RX   PubMed=11424192; DOI=10.1002/glia.1070;
RA   Cheepsunthorn P., Radov L., Menzies S., Reid J., Connor J.R.;
RT   "Characterization of a novel brain-derived microglial cell line
RT   isolated from neonatal rat brain.";
RL   Glia 35:53-62(2001).
//
RX   PubMed=22121004; DOI=10.1002/pmic.201100398;
RA   Bell-Temin H., Barber D.S., Zhang P., Liu B., Stevens S.M. Jr.;
RT   "Proteomic analysis of rat microglia establishes a high-confidence
RT   reference data set of over 3000 proteins.";
RL   Proteomics 12:246-250(2012).
//
RX   PubMed=22651808; DOI=10.1186/1742-2094-9-115;
RA   Stansley B., Post J., Hensley K.;
RT   "A comparative review of cell culture systems for the study of
RT   microglial biology in Alzheimer's disease.";
RL   J. Neuroinflamm. 9:115.1-115.8(2012).
//