Cellosaurus logo
expasy logo

Cellosaurus HMEEC-1 (CVCL_0E44)

[Text version]
Cell line name HMEEC-1
Synonyms HEI-HMEEC-1; HEI-HMEEC; Human Middle Ear Epithelial Cell line-1
Accession CVCL_0E44
Resource Identification Initiative To cite this cell line use: HMEEC-1 (RRID:CVCL_0E44)
Comments Group: Patented cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); PTA-81.
Doubling time: 23.8 hours (PubMed=12090706).
Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Derived from site: In situ; Ear, middle ear; UBERON=UBERON_0001756.
Cell type: Epithelial cell; CL=CL_0000066.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Age unspecified
Category Transformed cell line
STR profile Source(s): ATCC=CRL-13012

Markers:
AmelogeninX,Y
CSF1PO11
D5S81810,13
D7S82010,11
D13S31710,11
D16S53912,13
TH016,7
TPOX9,11
vWA16,17

Run an STR similarity search on this cell line
Publications

Patent=US6358688
Lim D.J., Chun Y.-M., Rhim J.S.
Immortalized human middle ear epithelial cell lines.
Patent number US6358688, 19-Mar-2002

PubMed=12090706; DOI=10.1177/000348940211100606
Chun Y.-M., Moon S.-K., Lee H.-Y., Webster P., Brackmann D.E., Rhim J.S., Lim D.J.
Immortalization of normal adult human middle ear epithelial cells using a retrovirus containing the E6/E7 genes of human papillomavirus type 16.
Ann. Otol. Rhinol. Laryngol. 111:507-517(2002)

PubMed=21901615; DOI=10.1007/978-1-4614-0254-1_2
Lim D.J., Moon S.-K.
Establishment of cell lines from the human middle and inner ear epithelial cells.
Adv. Exp. Med. Biol. 720:15-25(2011)

Cross-references
Cell line collections (Providers) ATCC; CRL-13012 - Discontinued
Biological sample resources BioSample; SAMN03471351
Encyclopedic resources Wikidata; Q54889922
Entry history
Entry creation10-Apr-2015
Last entry update10-Sep-2024
Version number14