ID   HS-23
AC   CVCL_0E35
SY   HS23
DR   ATCC; CRL-2495
DR   Wikidata; Q54896268
RX   Patent=US7129086;
RX   PubMed=7849321;
RX   PubMed=20924730;
CC   Population: Caucasian.
CC   Transfected with: UniProtKB; P03126; Human papillomavirus type 16 protein E6.
CC   Transfected with: UniProtKB; P03129; Human papillomavirus type 16 protein E7.
CC   Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
CC   Discontinued: ATCC; CRL-2495; true.
CC   Derived from site: In situ; Bone marrow, stroma; UBERON=UBERON_0007195.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_3720 ! HS-5
OI   CVCL_0E34 ! HS-27
SX   Male
AG   30Y
CA   Transformed cell line
DT   Created: 10-04-15; Last updated: 05-10-23; Version: 16
//
RX   Patent=US7129086;
RA   Torok-Storb B., Roecklein B.A., Johnson G.;
RT   "Human marrow stromal cell lines which sustain hematopoiesis.";
RL   Patent number US7129086, 31-Oct-2006.
//
RX   PubMed=7849321; DOI=10.1182/blood.V85.4.997.bloodjournal854997;
RA   Roecklein B.A., Torok-Storb B.;
RT   "Functionally distinct human marrow stromal cell lines immortalized by
RT   transduction with the human papilloma virus E6/E7 genes.";
RL   Blood 85:997-1005(1995).
//
RX   PubMed=20924730; DOI=10.1007/s12185-010-0698-2;
RA   Sakai A., Oda M., Itagaki M., Yoshida N., Arihiro K., Kimura A.;
RT   "Establishment of an HS23 stromal cell-dependent myeloma cell line:
RT   fibronectin and IL-6 are critical.";
RL   Int. J. Hematol. 92:598-608(2010).
//