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Cellosaurus NZM087 (CVCL_0D47)

[Text version]
Cell line name NZM087
Synonyms NZM87
Accession CVCL_0D47
Resource Identification Initiative To cite this cell line use: NZM087 (RRID:CVCL_0D47)
Comments Omics: Deep exome analysis.
Omics: Transcriptome analysis by RNAseq.
Sequence variations
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Homozygous (PubMed=32567790).
  • Mutation; HGNC; HGNC:7765; NF1; Simple; p.His1170Tyr; Zygosity=Unspecified (PubMed=32567790).
  • Mutation; HGNC; HGNC:8803; PDGFRA; Simple; p.Glu996Lys (c.2986G>A); ClinVar=VCV000822435; Zygosity=Heterozygous (PubMed=32567790).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-146C>T (c.250C>T) (C250T); Zygosity=Unspecified; Note=In promoter (PubMed=32567790).
HLA typing Source: PubMed=32567790
Class I
HLA-AA*02:01,03:01
HLA-BB*07:02,14:02
HLA-CC*07:02,08:02
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): PubMed=32567790

Markers:
AmelogeninX,Y
CSF1PO11,13
D2S133820,24
D3S135814,15
D5S81811
D7S82010,12
D8S117911,13
D13S31711
D16S53911,13
D18S5116,17
D19S43312,13
D21S1130,32.2
FGA23,25
TH016,8
TPOX8
vWA19,20

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Publications

PubMed=32567790; DOI=10.1111/pcmr.12908; PMCID=PMC7818249
Tran K.B., Gimenez G., Tsai P., Kolekar S., Rodger E.J., Chatterjee A., Jabed A., Shih J.-H., Joseph W.R., Marshall E.S., Wang Q., Print C.G., Eccles M.R., Baguley B.C., Shepherd P.R.
Genomic and signalling pathway characterization of the NZM panel of melanoma cell lines: a valuable model for studying the impact of genetic diversity in melanoma.
Pigment Cell Melanoma Res. 34:136-143(2021)

Cross-references
Cell line databases/resources cancercelllines; CVCL_0D47
Biological sample resources BioSample; SAMN14558354
Encyclopedic resources Wikidata; Q54931629
Entry history
Entry creation10-Apr-2015
Last entry update19-Dec-2024
Version number8