• Mutation; VGNC; 43761; NF1; Simple; p.Pro1599fs (c.4795delCinsTT); Zygosity=Heterozygous (PubMed=31175136).
  

PubMed=3434911
Wolfe L.G., Oliver J.L. III, Smith B.B., Toivio-Kinnucan M.A., Powers R.D., Brawner W.R., Henderson R.A., Hankes G.H.
Biologic characterization of canine melanoma cell lines.
Am. J. Vet. Res. 48:1642-1648(1987)

PubMed=8239507
Ahern T.E., Bird R.C., Church Bird A.E., Wolfe L.G.
Overexpression of c-erbB-2 and c-myc but not c-ras, in canine melanoma cell lines, is associated with metastatic potential in nude mice.
Anticancer Res. 13:1365-1371(1993)

PubMed=15965647; DOI=10.1007/s00262-005-0025-6
Alexander A.N., Huelsmeyer M.K., Mitzey A., Dubielzig R.R., Kurzman I.D., MacEwen E.G., Vail D.M.
Development of an allogeneic whole-cell tumor vaccine expressing xenogeneic gp100 and its implementation in a phase II clinical trial in canine patients with malignant melanoma.
Cancer Immunol. Immunother. 55:433-442(2006)

PubMed=21908323; DOI=10.1177/1040638711408064
O'Donoghue L.E., Rivest J.P., Duval D.L.
Polymerase chain reaction-based species verification and microsatellite analysis for canine cell line validation.
J. Vet. Diagn. Invest. 23:780-785(2011)

PubMed=22901430; DOI=10.1016/j.jcpa.2012.07.001
Chon E., Thompson V., Schmid S., Stein T.J.
Activation of the canonical Wnt/beta-catenin signalling pathway is rare in canine malignant melanoma tissue and cell lines.
J. Comp. Pathol. 148:178-187(2013)

PubMed=23410087; DOI=10.1111/vco.12019
Wilson-Robles H.M., Daly M., Pfent C., Sheppard-Olivares S.
Identification and evaluation of putative tumour-initiating cells in canine malignant melanoma cell lines.
Vet. Comp. Oncol. 13:60-69(2015)

PubMed=27257868; DOI=10.1371/journal.pone.0156689
Maeda J., Froning C.E., Brents C.A., Rose B.J., Thamm D.H., Kato T.A.
Intrinsic radiosensitivity and cellular characterization of 27 canine cancer cell lines.
PLoS ONE 11:E0156689-E0156689(2016)

PubMed=27197945; DOI=10.1111/vco.12192
Fowles J.S., Dailey D.D., Gustafson D.L., Thamm D.H., Duval D.L.
The Flint Animal Cancer Center (FACC) canine tumour cell line panel: a resource for veterinary drug discovery, comparative oncology and translational medicine.
Vet. Comp. Oncol. 15:481-492(2017)

PubMed=31175136; DOI=10.1158/1535-7163.MCT-18-1346
Das S., Idate R., Cronise K.E., Gustafson D.L., Duval D.L.
Identifying candidate druggable targets in canine cancer cell lines using whole exome sequencing.
Mol. Cancer Ther. 18:1460-1471(2019)