Cellosaurus cell line PT6216 (CVCL

Cross-references
Cell line name	PT6216
Accession	CVCL_0C59
Resource Identification Initiative	To cite this cell line use: PT6216 (RRID:CVCL_0C59)
Comments	Derived from site: In situ; Esophagus; UBERON=UBERON_0001043.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273Cys (c.817C>T); ClinVar=VCV000043594; Zygosity=Homozygous (PubMed=25070024).
Disease	Esophageal adenocarcinoma (NCIt: C4025) Adenocarcinoma of the esophagus (ORDO: Orphanet_99976)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual	CVCL_0C58 ! LN6216c
Sex of cell	Male
Age at sampling	46Y
Category	Cancer cell line
Publications	PubMed=25070024; DOI=10.1007/s00423-014-1235-1 Drenckhan A., Grob T., Dupree A., Dohrmann T., Mann O., Izbicki J.R., Gros S.J. Esophageal carcinoma cell line with high EGFR polysomy is responsive to gefitinib. Langenbecks Arch. Surg. 399:879-888(2014)
Cell line databases/resources	cancercelllines; CVCL_0C59
Encyclopedic resources	Wikidata; Q54948657
Polymorphism and mutation databases	Cosmic; 2218354
Entry history
Entry creation	10-Apr-2015
Last entry update	19-Dec-2024
Version number	12