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Cellosaurus NZM085 (CVCL_0B56)

[Text version]
Cell line name NZM085
Synonyms NZM85
Accession CVCL_0B56
Resource Identification Initiative To cite this cell line use: NZM085 (RRID:CVCL_0B56)
Comments Omics: Deep exome analysis.
Omics: Transcriptome analysis by RNAseq.
Sequence variations
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (PubMed=32567790).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (PubMed=32567790).
HLA typing Source: PubMed=32567790
Class I
HLA-AA*02:01,03:01
HLA-BB*07:02,07:02
HLA-CC*07:02,07:02
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): PubMed=32567790

Markers:
AmelogeninX,Y
CSF1PO10
D2S133817
D3S135816,18
D5S81812
D7S82011,13
D8S117914
D13S3178,12
D16S5398,11
D18S5115,17
D19S43313
D21S1130.2,31
FGA21,22
TH019
TPOX8,11
vWA18

Run an STR similarity search on this cell line
Publications

PubMed=23755070; DOI=10.3389/fgene.2013.00097; PMCID=PMC3668138
Kim J.E., Leung E.Y., Baguley B.C., Finlay G.J.
Heterogeneity of expression of epithelial-mesenchymal transition markers in melanocytes and melanoma cell lines.
Front. Genet. 4:97.1-97.8(2013)

PubMed=32567790; DOI=10.1111/pcmr.12908; PMCID=PMC7818249
Tran K.B., Gimenez G., Tsai P., Kolekar S., Rodger E.J., Chatterjee A., Jabed A., Shih J.-H., Joseph W.R., Marshall E.S., Wang Q., Print C.G., Eccles M.R., Baguley B.C., Shepherd P.R.
Genomic and signalling pathway characterization of the NZM panel of melanoma cell lines: a valuable model for studying the impact of genetic diversity in melanoma.
Pigment Cell Melanoma Res. 34:136-143(2021)

Cross-references
Cell line databases/resources cancercelllines; CVCL_0B56
Biological sample resources BioSample; SAMN14558352
Encyclopedic resources Wikidata; Q54931627
Entry history
Entry creation10-Apr-2015
Last entry update19-Dec-2024
Version number8