ID   NZM076
AC   CVCL_0B51
SY   NZM76
DR   cancercelllines; CVCL_0B51
DR   Cosmic; 2141928
DR   Wikidata; Q54931617
RX   PubMed=24455489;
RX   PubMed=32567790;
CC   Sequence variation: Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (PubMed=32567790).
CC   Sequence variation: Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (PubMed=32567790).
ST   Source(s): PubMed=32567790
ST   Amelogenin: X
ST   CSF1PO: 12
ST   D13S317: 9,12
ST   D16S539: 8,9
ST   D18S51: 12,15
ST   D19S433: 13,14
ST   D21S11: 32.2
ST   D2S1338: 17,18
ST   D3S1358: 14,16
ST   D5S818: 11
ST   D7S820: 8,11
ST   D8S1179: 11,13
ST   FGA: 23,24
ST   TH01: 7,9
ST   TPOX: 8,11
ST   vWA: 16,19
DI   NCIt; C3224; Melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
CA   Cancer cell line
DT   Created: 10-04-15; Last updated: 19-12-24; Version: 8
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RX   PubMed=24455489; DOI=10.3389/fonc.2013.00333; PMCID=PMC3888952;
RA   D'mello S.A.N., Flanagan J.U., Green T.N., Leung E.Y.,
RA   Askarian-Amiri M.E., Joseph W.R., McCrystal M.R., Isaacs R.J.,
RA   Shaw J.H.F., Furneaux C.E., During M.J., Finlay G.J., Baguley B.C.,
RA   Kalev-Zylinska M.L.;
RT   "Evidence that GRIN2A mutations in melanoma correlate with decreased
RT   survival.";
RL   Front. Oncol. 3:333.1-333.9(2014).
//
RX   PubMed=32567790; DOI=10.1111/pcmr.12908; PMCID=PMC7818249;
RA   Tran K.B., Gimenez G., Tsai P., Kolekar S., Rodger E.J.,
RA   Chatterjee A., Jabed A., Shih J.-H., Joseph W.R., Marshall E.S.,
RA   Wang Q., Print C.G., Eccles M.R., Baguley B.C., Shepherd P.R.;
RT   "Genomic and signalling pathway characterization of the NZM panel of
RT   melanoma cell lines: a valuable model for studying the impact of
RT   genetic diversity in melanoma.";
RL   Pigment Cell Melanoma Res. 34:136-143(2021).
//