ID   228A
AC   CVCL_0B43
DR   cancercelllines; CVCL_0B43
DR   Cosmic; 2163761
DR   Wikidata; Q54583373
RX   PubMed=9620551;
RX   PubMed=24812411;
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gly279Glu (c.836G>A); ClinVar=VCV000419454; Zygosity=Unspecified (PubMed=9620551).
DI   NCIt; C3752; Embryonal carcinoma
DI   ORDO; Orphanet_180226; Embryonal carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   Age unspecified
CA   Cancer cell line
DT   Created: 10-04-15; Last updated: 19-12-24; Version: 10
//
RX   PubMed=9620551; DOI=10.1038/sj.onc.1201770;
RA   Houldsworth J., Xiao H., Murty V.V.V.S., Chen W.-Y., Ray B., Reuter V.E.,
RA   Bosl G.J., Chaganti R.S.K.;
RT   "Human male germ cell tumor resistance to cisplatin is linked to TP53
RT   gene mutation.";
RL   Oncogene 16:2345-2349(1998).
//
RX   PubMed=24812411; DOI=10.1158/1078-0432.CCR-13-2868;
RA   Feldman D.R., Iyer G., Van Alstine L., Patil S., Al-Ahmadie H.,
RA   Reuter V.E., Bosl G.J., Chaganti R.S.K., Solit D.B.;
RT   "Presence of somatic mutations within PIK3CA, AKT, RAS, and FGFR3 but
RT   not BRAF in cisplatin-resistant germ cell tumors.";
RL   Clin. Cancer Res. 20:3712-3720(2014).
//