Cellosaurus cell line Caki-dTub (CVCL

Cross-references
Cell line name	Caki-dTub
Accession	CVCL_0B30
Resource Identification Initiative	To cite this cell line use: Caki-dTub (RRID:CVCL_0B30)
Comments	Population: Caucasian. Selected for resistance to: ChEBI; CHEBI:88246; 2'-deoxytubercidin. Derived from site: Metastatic; Skin; UBERON=UBERON_0002097.
Sequence variations	Mutation; HGNC; 9884; RB1; Simple; p.Leu98Pro (c.293T>C); ClinVar=VCV001502192; Zygosity=Heterozygous (from parent cell line).
Disease	Clear cell renal cell carcinoma (NCIt: C4033) Clear cell renal carcinoma (ORDO: Orphanet_319276)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0234 (Caki-1)
Sex of cell	Male
Age at sampling	49Y
Category	Cancer cell line
Publications	CLPUB00226 Pan B.-F., Nelson J.A. Multidrug resistance and collateral sensitivity in a human renal carcinoma selected for resistance to 2'-deoxytubercidin. UroOncology 1:165-174(2001) PubMed=17009030; DOI=10.1007/s00280-006-0351-1 Pan B.-F., Nelson J.A. Dihydrodiol dehydrogenase in drug resistance and sensitivity of human carcinomas. Cancer Chemother. Pharmacol. 59:697-702(2007)
Anatomy/cell type resources	BTO; BTO:0005559
Encyclopedic resources	Wikidata; Q54808380
Entry history
Entry creation	10-Apr-2015
Last entry update	29-Jun-2023
Version number	12