Cell line name |
Capan1M9 |
Accession |
CVCL_0A59 |
Resource Identification Initiative |
To cite this cell line use: Capan1M9 (RRID:CVCL_0A59) |
Comments |
Population: Caucasian. Characteristics: Highly migratory cell subclone of Capan-1. Derived from site: Metastatic; Liver; UBERON=UBERON_0002107. |
Sequence variations |
- Mutation; HGNC; HGNC:1101; BRCA2; Simple; p.Ser1982Argfs*22 (c.5946delT) (6174delT); ClinVar=VCV000009325; Zygosity=Hemizygous (from parent cell line).
- Mutation; HGNC; HGNC:4039; FZD10; Simple; p.Asn54Lys (c.162C>A); Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; HGNC:23671; GLT6D1; Simple; p.Trp198Ter (c.593G>A); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:4593; GRM1; Simple; p.Tyr486Ter (c.1458C>A); Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; HGNC:6844; MAP2K4; Simple; p.Glu221Ter (c.661G>T); Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; HGNC:6770; SMAD4; Simple; p.Ser343Ter (c.1028C>G); ClinVar=VCV000822036; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; HGNC:25082; SMAP2; Simple; p.Ser255Ter (c.764C>G); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ala159Val (c.476C>T); ClinVar=VCV000458545; Zygosity=Homozygous (from parent cell line).
|
Disease |
Pancreatic ductal adenocarcinoma (NCIt: C9120) |
Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
Hierarchy |
Parent: CVCL_0237 (Capan-1) |
Sex of cell |
Male |
Age at sampling |
40Y |
Category |
Cancer cell line |
Publications | PubMed=22109279; DOI=10.1007/s13577-011-0037-9 Ding Q., Yoshimitsu M., Kuwahata T., Maeda K., Hayashi T., Obara T., Miyazaki Y., Matsubara S., Natsugoe S., Takao S. Establishment of a highly migratory subclone reveals that CD133 contributes to migration and invasion through epithelial-mesenchymal transition in pancreatic cancer. Hum. Cell 25:1-8(2012) |
Cross-references |
Cell line databases/resources |
cancercelllines; CVCL_0A59
|
Encyclopedic resources |
Wikidata; Q54808592
|
Entry history |
Entry creation | 10-Apr-2015 |
Last entry update | 19-Dec-2024 |
Version number | 16 |
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