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Cellosaurus Hs 819.T (CVCL_0928)

[Text version]
Cell line name Hs 819.T
Synonyms Hs-819-T; Hs819.T; Hs819T; HS819T
Accession CVCL_0928
Resource Identification Initiative To cite this cell line use: Hs 819.T (RRID:CVCL_0928)
Comments Problematic cell line: Misclassified. Originally thought to be a chondrosarcoma cell line but using a variety of omics methods was shown to be a a fibroblastic cell line (DOI=10.1101/166199; DepMap=ACH-000224).
Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).
Population: Caucasian.
Omics: Deep exome analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Bone; UBERON=UBERON_0002481.
Cell type: Fibroblast; CL=CL_0000057.
Genome ancestry Source: PubMed=30894373

Origin% genome
African0
Native American0
East Asian, North1.16
East Asian, South0.22
South Asian1.63
European, North67.05
European, South29.93
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_S072 ! Hs 819.Sk
Sex of cell Male
Age at sampling 60Y
Category Undefined cell line type
STR profile Source(s): ATCC=CRL-7891

Markers:
AmelogeninX
CSF1PO10,12
D2S133817,19,24
D3S135815,16
D5S81811,12
D7S8209,12
D8S117910,13
D13S3178,12
D16S5399,10,13
D18S5112,14,18
D19S43313,14
D21S1128,29,32.2
FGA20,22,24,26
Penta D9,12,17
Penta E7,10,13,14
TH017,9.3
TPOX8,11
vWA17,19

Run an STR similarity search on this cell line
Publications

PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.-Y.K., Yu J.-J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N.-X., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M.L., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

DOI=10.1101/166199
de Weck A., Bitter H., Kauffmann A.
Fibroblasts cell lines misclassified as cancer cell lines.
bioRxiv 2017:166199-166199(2017)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. 3rd, Barretina J.G., Gelfand E.T., Bielski C.M., Li H.-X., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y.-L., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cross-references
Cell line collections (Providers) ATCC; CRL-7891
Cell line databases/resources CLO; CLO_0004135
cancercelllines; CVCL_0928
Cell_Model_Passport; SIDM01699
DepMap; ACH-000224
Biological sample resources BioSample; SAMN03471113
BioSample; SAMN10988131
Chemistry resources PharmacoDB; Hs819_T_597_2019
Encyclopedic resources Wikidata; Q54896083
Gene expression databases ArrayExpress; E-MTAB-2770
GEO; GSM887118
GEO; GSM888189
GEO; GSM1676366
GEO; GSM1701696
Polymorphism and mutation databases IARC_TP53; 30063
LiGeA; CCLE_521
Progenetix; CVCL_0928
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number23