ID Kasumi-2 AC CVCL_0590 SY KASUMI-2; KASUMI2; Kasumi2 DR EFO; EFO_0002224 DR ArrayExpress; E-MTAB-38 DR ArrayExpress; E-MTAB-2770 DR BioSample; SAMN03473522 DR BioSample; SAMN10988450 DR cancercelllines; CVCL_0590 DR Cell_Model_Passport; SIDM01694 DR Cosmic; 1130249 DR Cosmic; 1524843 DR DepMap; ACH-000728 DR DSMZ; ACC-526 DR DSMZCellDive; ACC-526 DR GEO; GSM236786 DR GEO; GSM236822 DR GEO; GSM887198 DR GEO; GSM888271 DR GEO; GSM4254130 DR GEO; GSM5137720 DR GEO; GSM5137758 DR IARC_TP53; 28402 DR IGRhCellID; Kasumi2 DR JCRB; JCRB1395 DR LiGeA; CCLE_042 DR PharmacoDB; KASUMI2_734_2019 DR PRIDE; PXD023662 DR Progenetix; CVCL_0590 DR Wikidata; Q54899516 RX PubMed=10739008; RX PubMed=11226526; RX PubMed=20215515; RX PubMed=22460905; RX PubMed=26589293; RX PubMed=28196595; RX PubMed=29786757; RX PubMed=30285677; RX PubMed=30629668; RX PubMed=30894373; RX PubMed=31068700; RX PubMed=31305009; RX PubMed=31978347; RX PubMed=32180206; RX PubMed=35124168; RX PubMed=35354797; WW Info; MCLP; -; https://tcpaportal.org/mclp/ CC Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). CC Part of: MD Anderson Cell Lines Project. CC Population: Japanese. CC Doubling time: ~30 hours (DSMZ=ACC-526); ~45 hours (Note=Lot 01182019) (JCRB=JCRB1395). CC HLA typing: A*24:02,26:02; B*40:06,54:01; C*01:02,08:01; DQA1*03:02,04:01; DQB1*03:04,03:04; DRB1*09:01,11:01 (PubMed=26589293). CC Microsatellite instability: Stable (MSS) (PubMed=10739008; PubMed=11226526). CC Sequence variation: Gene fusion; HGNC; HGNC:8632; PBX1 + HGNC; HGNC:11633; TCF3; Name(s)=TCF3-PBX1, E2A-PBX1 (PubMed=32180206; PubMed=35354797; DepMap=ACH-000728). CC Sequence variation: Mutation; HGNC; HGNC:5173; HRAS; Simple; p.Gly13Ser (c.37G>A); ClinVar=VCV000376323; Zygosity=Heterozygous (DepMap=ACH-000728). CC Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Val14Leu (c.40G>T); Zygosity=Heterozygous (DepMap=ACH-000728). CC Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu11Gln (c.31G>C); ClinVar=VCV000041723; Zygosity=Heterozygous (DepMap=ACH-000728). CC Omics: Genomics; Whole exome sequencing. CC Omics: Phenotyping; Drug screening. CC Omics: Proteomics; Expression; Reverse-phase protein array. CC Omics: Proteomics; Quantitative. CC Omics: Transcriptomics; Microarray. CC Omics: Transcriptomics; RNAseq. CC Omics: Variations; SNP array analysis. CC Genome ancestry: African=0%; Native American=0.35%; East Asian, North=80.22%; East Asian, South=17.64%; South Asian=0%; European, North=1.01%; European, South=0.78% (PubMed=30894373). CC Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371. ST Source(s): DSMZ=ACC-526; JCRB=JCRB1395 ST Amelogenin: X (DSMZ=ACC-526) ST Amelogenin: X,Y (JCRB=JCRB1395) ST CSF1PO: 10,11 ST D13S317: 8,12,13 ST D16S539: 9,13 ST D18S51: 12,13 ST D19S433: 12,13 ST D21S11: 31.2,32.2 ST D2S1338: 17,24 ST D3S1358: 14,16 ST D5S818: 11,12 ST D7S820: 11,12 ST D8S1179: 13,14 ST FGA: 22,23 ST Penta D: 9,10 ST Penta E: 11,16 ST TH01: 8,10 ST TPOX: 8,11 ST vWA: 17,18 DI NCIt; C9140; Childhood B acute lymphoblastic leukemia DI NCIt; C80347; B acute lymphoblastic leukemia with t(1;19)(q23;p13.3) E2A-PBX1 (TCF3-PBX1) DI ORDO; Orphanet_585956; B-lymphoblastic leukemia/lymphoma with t(1;19)(q23;p13.3) OX NCBI_TaxID=9606; ! Homo sapiens (Human) SX Male AG 15Y CA Cancer cell line DT Created: 04-04-12; Last updated: 14-08-25; Version: 35 // RX PubMed=29786757; DOI=10.1007/s12185-018-2474-7; RA Tomoyasu, Chihiro RA Imamura, Toshihiko RA Tomii, Toshihiro RA Yano, Mio RA Asai, Daisuke RA Goto, Hiroaki RA Shimada, Akira RA Sanada, Masashi RA Iwamoto, Shotaro RA Takita, Junko RA Minegishi, Masayoshi RA Inukai, Takeshi RA Sugita, Kanji RA Hosoi, Hajime RT "Copy number abnormality of acute lymphoblastic leukemia cell lines RT based on their genetic subtypes."; RL Int. J. Hematol. 108:312-318(2018). // RX PubMed=35124168; DOI=10.1016/j.jsbmb.2022.106068; RA Tamai, Minori RA Kasai, Shin RA Akahane, Koshi RA Thu, Thao Nguyen RA Kagami, Keiko RA Komatsu, Chiaki RA Abe, Masako RA Watanabe, Atsushi RA Goi, Kumiko RA Miyake, Kunio RA Inaba, Toshiya RA Takita, Junko RA Goto, Hiroaki RA Minegishi, Masayoshi RA Iwamoto, Shotaro RA Sugita, Kanji RA Inukai, Takeshi RT "Glucocorticoid receptor gene mutations confer glucocorticoid RT resistance in B-cell precursor acute lymphoblastic leukemia."; RL J. Steroid Biochem. Mol. Biol. 218:106068.1-106068.12(2022). // RX PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103; RA Ghandi, Mahmoud RA Huang, Franklin W. RA Jane-Valbuena, Judit RA Kryukov, Gregory V. RA Lo, Christopher C. RA McDonald, E. Robert 3rd RA Barretina, Jordi Ginesta RA Gelfand, Ellen T. RA Bielski, Craig M. RA Li, Hao-Xin RA Hu, Kevin RA Andreev-Drakhlin, Alexander Y. RA Kim, Jaegil RA Hess, Julian M. RA Haas, Brian J. RA Aguet, Francois RA Weir, Barbara A. RA Rothberg, Michael V. RA Paolella, Brenton R. RA Lawrence, Michael Scott RA Akbani, Rehan RA Lu, Yi-Ling RA Tiv, Hong L. RA Gokhale, Prafulla C. RA de Weck, Antoine RA Mansour, Ali Amin RA Oh, Coyin RA Shih, Juliann RA Hadi, Kevin RA Rosen, Yanay RA Bistline, Jonathan RA Venkatesan, Kavitha RA Reddy, Anupama RA Sonkin, Dmitriy RA Liu, Manway RA Lehar, Joseph RA Korn, Joshua M. RA Porter, Dale A. RA Jones, Michael D. RA Golji, Javad RA Caponigro, Giordano RA Taylor, Jordan E. RA Dunning, Caitlin M. RA Creech, Amanda L. RA Warren, Allison C. RA McFarland, James M. RA Zamanighomi, Mahdi RA Kauffmann, Audrey RA Stransky, Nicolas RA Imielinski, Marcin RA Maruvka, Yosef E. RA Cherniack, Andrew D. RA Tsherniak, Aviad RA Vazquez, Francisca RA Jaffe, Jacob D. RA Lane, Andrew Alan RA Weinstock, David M. RA Johannessen, Cory M. RA Morrissey, Michael P. RA Stegmeier, Frank RA Schlegel, Robert RA Hahn, William Chun RA Getz, Gad RA Mills, Gordon B. RA Boehm, Jesse S. RA Golub, Todd Robert RA Garraway, Levi Alexander RA Sellers, William Raj RT "Next-generation characterization of the Cancer Cell Line RT Encyclopedia."; RL Nature 569:503-508(2019). // RX PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076; RA Li, Jun RA Zhao, Wei RA Akbani, Rehan RA Liu, Wen-Bin RA Ju, Zhen-Lin RA Ling, Shi-Yun RA Vellano, Christopher P. RA Roebuck, Paul RA Yu, Qing-Hua RA Eterovic, Agda Karina RA Byers, Lauren Averett RA Davies, Michael A. RA Deng, Wan-Leng RA Gopal, Y.N. Vashisht RA Chen, Guo RA von Euw, Erika Maria RA Slamon, Dennis Joseph RA Conklin, Dylan RA Heymach, John Victor RA Gazdar, Adi F. RA Minna, John D. RA Myers, Jeffrey N. RA Lu, Yi-Ling RA Mills, Gordon B. RA Liang, Han RT "Characterization of human cancer cell lines by reverse-phase protein RT arrays."; RL Cancer Cell 31:225-239(2017). // RX PubMed=31305009; DOI=10.1002/cam4.2356; PMCID=PMC6718581; RA Watanabe, Atsushi RA Inukai, Takeshi RA Kagami, Keiko RA Abe, Masako RA Takagi, Masatoshi RA Fukushima, Takashi RA Fukushima, Hiroko RA Nanmoku, Toru RA Terui, Kiminori RA Ito, Tatsuya RA Toki, Tsutomu RA Ito, Etsuro RA Fujimura, Junya RA Goto, Hiroaki RA Endo, Mikiya RA Look, Thomas RA Kamps, Mark P. RA Minegishi, Masayoshi RA Takita, Junko RA Inaba, Toshiya RA Takahashi, Hiroyuki RA Ohara, Akira RA Harama, Daisuke RA Shinohara, Tamao RA Somazu, Shinpei RA Oshiro, Hiroko RA Akahane, Koshi RA Goi, Kumiko RA Sugita, Kanji RT "Resistance of t(17;19)-acute lymphoblastic leukemia cell lines to RT multiagents in induction therapy."; RL Cancer Med. 8:5274-5288(2019). // RX PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027; RA Barretina, Jordi Ginesta RA Caponigro, Giordano RA Stransky, Nicolas RA Venkatesan, Kavitha RA Margolin, Adam A. RA Kim, Sungjoon RA Wilson, Christopher J. RA Lehar, Joseph RA Kryukov, Gregory V. RA Sonkin, Dmitriy RA Reddy, Anupama RA Liu, Manway RA Murray, Lauren RA Berger, Michael F. RA Monahan, John E. RA Morais, Paula RA Meltzer, Jodi RA Korejwa, Adam RA Jane-Valbuena, Judit RA Mapa, Felipa A. RA Thibault, Joseph RA Bric-Furlong, Eva RA Raman, Pichai RA Shipway, Aaron RA Engels, Ingo H. RA Cheng, Jill RA Yu, Guo-Ying K. RA Yu, Jian-Jun RA Aspesi, Peter Jr. RA de Silva, Melanie RA Jagtap, Kalpana RA Jones, Michael D. RA Wang, Li RA Hatton, Charles RA Palescandolo, Emanuele RA Gupta, Supriya RA Mahan, Scott RA Sougnez, Carrie RA Onofrio, Robert C. RA Liefeld, Ted RA MacConaill, Laura Eleanor RA Winckler, Wendy RA Reich, Michael RA Li, Nan-Xin RA Mesirov, Jill P. RA Gabriel, Stacey B. RA Getz, Gad RA Ardlie, Kristin RA Chan, Vivien RA Myer, Vic E. RA Weber, Barbara L. RA Porter, Jeff RA Warmuth, Markus RA Finan, Peter RA Harris, Jennifer L. RA Meyerson, Matthew Langer RA Golub, Todd Robert RA Morrissey, Michael P. RA Sellers, William Raj RA Schlegel, Robert RA Garraway, Levi Alexander RT "The Cancer Cell Line Encyclopedia enables predictive modelling of RT anticancer drug sensitivity."; RL Nature 483:603-607(2012). // RX PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878; RA Scholtalbers, Jelle RA Boegel, Sebastian RA Bukur, Thomas RA Byl, Marius RA Goerges, Sebastian RA Sorn, Patrick RA Loewer, Martin RA Sahin, Ugur RA Castle, John C. RT "TCLP: an online cancer cell line catalogue integrating HLA type, RT predicted neo-epitopes, virus and gene expression."; RL Genome Med. 7:118.1-118.7(2015). // RX PubMed=30629668; DOI=10.1371/journal.pone.0210404; PMCID=PMC6328144; RA Uphoff, Cord C. RA Pommerenke, Claudia RA Denkmann, Sabine A. RA Drexler, Hans Gunther RT "Screening human cell lines for viral infections applying RNA-Seq data RT analysis."; RL PLoS ONE 14:e0210404.1-e0210404.22(2019). // RX PubMed=31978347; DOI=10.1016/j.cell.2019.12.023; PMCID=PMC7339254; RA Nusinow, David Paul RA Szpyt, John RA Ghandi, Mahmoud RA Rose, Christopher M. RA McDonald, E. Robert 3rd RA Kalocsay, Marian RA Jane-Valbuena, Judit RA Gelfand, Ellen T. RA Schweppe, Devin Karl RA Jedrychowski, Mark P. RA Golji, Javad RA Porter, Dale A. RA Rejtar, Tomas RA Wang, Y. Karen RA Kryukov, Gregory V. RA Stegmeier, Frank RA Erickson, Brian K. RA Garraway, Levi Alexander RA Sellers, William Raj RA Gygi, Steven P. RT "Quantitative proteomics of the Cancer Cell Line Encyclopedia."; RL Cell 180:387-402.e16(2020). // RX PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675; RA Dutil, Julie RA Chen, Zhi-Hua RA Monteiro, Alvaro N.A. RA Teer, Jamie K. RA Eschrich, Steven A. RT "An interactive resource to probe genetic diversity and estimated RT ancestry in cancer cell lines."; RL Cancer Res. 79:1263-1273(2019). // RX PubMed=35354797; DOI=10.1038/s41467-022-29224-5; PMCID=PMC8967900; RA Leo, Isabelle Rose RA Aswad, Luay RA Stahl, Matthias RA Kunold, Elena RA Post, Frederik RA Erkers, Tom RA Struyf, Nona RA Mermelekas, Georgios RA Joshi, Rubin Narayan RA Gracia-Villacampa, Eva RA Ostling, Paivi RA Kallioniemi, Olli-Pekka RA Pokrovskaja Tamm, Katja RA Siavelis, Ioannis RA Lehtio, Janne RA Vesterlund, Mattias RA Jafari, Rozbeh RT "Integrative multi-omics and drug response profiling of childhood RT acute lymphoblastic leukemia cell lines."; RL Nat. Commun. 13:1691.1-1691.19(2022). // RX PubMed=10739008; DOI=10.1016/S0145-2126(99)00182-4; RA Inoue, Kaoru RA Kohno, Takashi RA Takakura, Satoshi RA Hayashi, Yasuhide RA Mizoguchi, Hideaki RA Yokota, Jun RT "Frequent microsatellite instability and BAX mutations in T cell acute RT lymphoblastic leukemia cell lines."; RL Leuk. Res. 24:255-262(2000). // RX PubMed=30285677; DOI=10.1186/s12885-018-4840-5; PMCID=PMC6167786; RA Tan, Kar-Tong RA Ding, Ling-Wen RA Sun, Qiao-Yang RA Lao, Zhen-Tang RA Chien, Wenwen RA Ren, Xi RA Xiao, Jin-Fen RA Loh, Xin-Yi RA Xu, Liang RA Lill, Michael RA Mayakonda, Anand RA Lin, De-Chen RA Yang, Henry He RA Koeffler, Harold Phillip RT "Profiling the B/T cell receptor repertoire of lymphocyte derived cell RT lines."; RL BMC Cancer 18:940.1-940.13(2018). // RX PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662; RA Rothenberg, S. Michael RA Mohapatra, Gayatry RA Rivera, Miguel N. RA Winokur, Daniel RA Greninger, Patricia RA Nitta, Mai RA Sadow, Peter M. RA Sooriyakumar, Gaya RA Brannigan, Brian W. RA Ulman, Matthew J. RA Perera, Rushika M. RA Wang, Rui RA Tam, Angela RA Ma, Xiao-Jun RA Erlander, Mark RA Sgroi, Dennis C. RA Rocco, James W. RA Lingen, Mark W. RA Cohen, Ezra E.W. RA Louis, David Neil RA Settleman, Jeffrey RA Haber, Daniel Arie RT "A genome-wide screen for microdeletions reveals disruption of RT polarity complex genes in diverse human cancers."; RL Cancer Res. 70:2158-2164(2010). // RX PubMed=11226526; DOI=10.1016/S0145-2126(00)00121-1; RA Inoue, Kaoru RA Kohno, Takashi RA Takakura, Satoshi RA Hayashi, Yasuhide RA Mizoguchi, Hideaki RA Yokota, Jun RT "Corrigendum to 'Frequent microsatellite instability and BAX mutations RT in T cell acute lymphoblastic leukemia cell lines' Leukemia Research 24 RT (2000), 255-262."; RL Leuk. Res. 25:275-278(2001). // RX PubMed=32180206; DOI=10.1007/s13577-020-00347-5; PMCID=PMC7324421; RA Kasai, Fumio RA Asou, Hiroya RA Ozawa, Midori RA Kobayashi, Kazuhiko RA Kuramitsu, Hiroyuki RA Satoh, Motonobu RA Kohara, Arihiro RA Kaneko, Yasuhiko RA Kawamura, Machiko RT "Kasumi leukemia cell lines: characterization of tumor genomes with RT ethnic origin and scales of genomic alterations."; RL Hum. Cell 33:868-876(2020). //