| Cell line name |
Jurkat Wurzburg |
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| Synonyms |
Wurzburg; Jurkat JR; JR |
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| Accession |
CVCL_0584 |
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| Resource Identification Initiative |
To cite this cell line use: Jurkat Wurzburg (RRID:CVCL_0584) |
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| Comments |
Population: Caucasian.
Doubling time: 16.6 +- 2 hours (PubMed=10468210).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: T-cell; CL=CL_0000084. |
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| Sequence variations |
- Mutation; HGNC; HGNC:959; BAX; Simple; p.Glu41Argfs*19 (c.121delG); ClinVar=VCV000009512; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:959; BAX; Simple; p.Glu41Glyfs*33 (c.121dupG); ClinVar=VCV000009511; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:16712; FBXW7; Simple; p.Arg505Cys (c.1513C>T); ClinVar=VCV000069961; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:6079; INPP5D; Simple; p.Gln345Ter (c.1033C>T); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:6079; INPP5D; Simple; c.1097+1065_1097+1112del47; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:7325; MSH2; Simple; p.Arg711Ter (c.2131C>T); ClinVar=VCV000090903; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; HGNC:7329; MSH6; Simple; p.Phe1088Serfs*2 (c.3261delC); ClinVar=VCV000089363; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg196Ter (c.586C>T); ClinVar=VCV000043589; Zygosity=Heterozygous (from parent cell line).
|
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| Disease |
Childhood T acute lymphoblastic leukemia (NCIt: C7953)
Precursor T-cell acute lymphoblastic leukemia (ORDO: Orphanet_99861) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Hierarchy |
Parent: CVCL_0065 (Jurkat) |
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| Sex of cell |
Male |
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| Age at sampling |
14Y |
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| Category |
Cancer cell line |
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| Publications | PubMed=7526398; DOI=10.1073/pnas.91.24.11527; PMCID=PMC45264
Anderson M.T., Staal F.J.T., Gitler C., Herzenberg L.A., Herzenberg L.A.
Separation of oxidant-initiated and redox-regulated steps in the NF-kappa B signal transduction pathway.
Proc. Natl. Acad. Sci. U.S.A. 91:11527-11531(1994) PubMed=10468210; DOI=10.1016/S0891-5849(99)00074-X
Schoene N.W., Kamara K.S.
Population doubling time, phosphatase activity, and hydrogen peroxide generation in Jurkat cells.
Free Radic. Biol. Med. 27:364-369(1999) |
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| Cross-references |
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| Cell line databases/resources |
MCCL; MCC:0000490
cancercelllines; CVCL_0584
|
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| Encyclopedic resources |
Wikidata; Q54899145
|
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| Entry history |
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| Entry creation | 04-Apr-2012 |
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| Last entry update | 19-Dec-2024 |
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| Version number | 22 |
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